Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 7/20 | 0.62 |
| ▸ | KDM4A | O75164 | 1/20 | 0.59 |
| ▸ | KDM5A | P29375 | 1/20 | 0.59 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.59 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.59 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.59 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15312924 | 0.92 | ALOX5 (0.71) | ALOX5KDM4AKDM5AKDM4CPHF8 | |
| SCHEMBL1520687 | 0.84 | ALOX5 (0.65) | ALOX5KDM4AKDM5AKDM4CPHF8 | |
| SCHEMBL28929226 | 0.80 | SIGMAR1 (0.64) | ALOX5KDM4AKDM5AKDM4CPHF8 | |
| SCHEMBL27210146 | 0.80 | SIGMAR1 (0.64) | ALOX5KDM4AKDM5AKDM4CPHF8 | |
| SCHEMBL28457555 | 0.80 | SIGMAR1 (0.64) | ALOX5KDM4AKDM5AKDM4CPHF8 | |
| SCHEMBL18758200 | 0.79 | SIGMAR1 (0.62) | ALOX5KDM4AKDM5AKDM4CPHF8 | |
| Toluene SCHEMBL3904976 | 0.79 | REN (0.53) | ALOX5KDM4AKDM5AKDM4CPHF8 | |
| SCHEMBL27210158 | 0.78 | SIGMAR1 (0.61) | ALOX5SIGMAR1MAPTRXFP1ADRA1A | |
| SCHEMBL25337443 | 0.78 | SIGMAR1 (0.52) | ALOX5KDM4AKDM5AKDM4CPHF8 | |
| SCHEMBL1955414 | 0.78 | SIGMAR1 (0.56) | ALOX5KDM4AKDM5AKDM4CPHF8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130131085-A1 | CYTOCHROME P450 OXIDASE INHIBITORS AND USES THEREOF | ABBOTT LABORATORIES (US) | 2013-05-23 | — | — | US | disclosed |
| US-20120083490-A1 | CYTOCHROME P450 OXIDASE INHIBITORS AND USES THEREOF | ABBOTT LABORATORIES (US) | 2012-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120083490-A1 | CYTOCHROME P450 OXIDASE INHIBITORS AND USES THEREOF | CYP3A43, CYP3A5, POR | ALOX5 215/4885KDM4A 1020/4885KDM5A 792/4885 |
| US-20130131085-A1 | CYTOCHROME P450 OXIDASE INHIBITORS AND USES THEREOF | CYP3A43, CYP3A5, POR | ALOX5 215/4885KDM4A 1020/4885KDM5A 792/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.