SCHEMBL4585151

SCHEMBL4585151

c1ccc(-c2occ3ccccc23)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.39
PTGS1 P23219 1/20 0.39
ABCG2 Q9UNQ0 4/20 0.38
KDM4E B2RXH2 3/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
GPR55 Q9Y2T6 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
PTGES O14684 1/20 0.37
ALDH1A1 P00352 3/20 0.36
CYP2A6 P11509 1/20 0.36
TSHR P16473 1/20 0.36
HSD17B10 Q99714 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
NR4A2 P43354 1/20 0.35
MAPT P10636 1/20 0.35
HPGD P15428 1/20 0.35
MPI P34949 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27883549 0.92 ALOX5 (0.36) ALOX5PTGS1ABCG2KDM4ENPC1
Furan SCHEMBL28154172 0.90 KDM4E (0.36) ALOX5PTGS1ABCG2KDM4ENPC1
Benzofuran SCHEMBL28158538 0.87 MAOA (0.39) ALOX5PTGS1ABCG2KDM4ENPC1
SCHEMBL27279704 0.86 HDAC1 (0.38) ALOX5PTGS1KDM4EL3MBTL1PTGES
SCHEMBL28475533 0.84 ALDH1A1 (0.39) ALOX5PTGS1KDM4EGPR55L3MBTL1
SCHEMBL23029708 0.84 ENPP3 (0.43) KDM4ENPC1RAB9AALDH1A1TSHR
SCHEMBL10902564 0.84 MAPT (0.41) KDM4ENPC1RAB9AGPR55L3MBTL1
SCHEMBL9427742 0.84 MITF (0.44) KDM4ENPC1RAB9AALDH1A1HSD17B10
SCHEMBL712886 0.84 ENPP3 (0.32) ALOX5PTGS1ALDH1A1CYP2A6TSHR
SCHEMBL27678582 0.84 ALDH1A1 (0.41) KDM4ENPC1RAB9AALDH1A1CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 228 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122080034-A Polycyclic aromatic compound and organic electroluminescent element 2026-05-26 CN disclosed
CN-122059973-A Polycyclic aromatic compound, material for organic device, organic electroluminescent element, display device, and lighting device 爱思开新材料捷恩智株式会社 2026-05-19 CN disclosed
EP-4663642-A1 POLYCYCLIC AROMATIC COMPOUND Kyoto University (JP) 2025-12-17 EP disclosed
US-12473315-B2 Polycyclic aromatic compound KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2025-11-18 US disclosed
CN-120157693-A Polycyclic aromatic compound and organic electroluminescent element 爱思开新材料捷恩智株式会社 2025-06-17 CN disclosed
CN-120118107-A Polycyclic aromatic compound and organic electroluminescent element 爱思开新材料捷恩智株式会社 2025-06-10 CN disclosed
CN-120040479-A Polycyclic aromatic compound and organic electroluminescent element 爱思开新材料捷恩智株式会社 2025-05-27 CN disclosed
CN-119930662-A Polycyclic aromatic compound, organic electroluminescent element, display device, and lighting device 爱思开新材料捷恩智株式会社 2025-05-06 CN disclosed
US-20250081847-A1 POLYCYCLIC AROMATIC COMPOUND KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2025-03-06 US disclosed
CN-119504805-A Polycyclic aromatic compound, organic electroluminescent element, and display device or lighting device 国立大学法人京都大学 2025-02-25 CN disclosed
EP-1382598-A1 NOVEL HETEROCYCLIC DERIVATIVES Takeda Chemical Industries, Ltd. (JP) 2004-01-21 EP disclosed
CN-1394835-A Perylene derivative synthesis method, perylene derivative and organic EL element TDK CORP (JP) 2003-02-05 CN disclosed
EP-0605127-B1 Overcoating for multilayered organic photoreceptors containing a stabilizer and charge transport molecules XEROX CORP (US) 1997-07-02 EP disclosed
US-5401615-A Overcoating for multilayered organic photoreceptors containing a stabilizer and charge transport molecules XEROX CORPORATION (US) 1995-03-28 US disclosed
EP-0605127-A1 Overcoating for multilayered organic photoreceptors containing a stabilizer and charge transport molecules XEROX CORPORATION (US) 1994-07-06 EP disclosed
CN-1074219-A New 10-hydroxyl pheophytin a CHEIL FOODS & CHEM (KR) 1993-07-14 CN disclosed
EP-0186303-B1 ELECTROPHOTOGRAPHIC IMAGING MEMBERS XEROX CORPORATION (US) 1989-06-07 EP disclosed
EP-0234570-A2 Photopolymerizable composition, photosensitive element with that composition, and process for the production of a lithographic printing plate using this element BASF Aktiengesellschaft (DE) 1987-09-02 EP disclosed
US-4599286-A ELECTROGRAPHY XEROX CORPORATION (US) 1986-07-08 US disclosed
EP-0186303-A1 Electrophotographic imaging members XEROX CORPORATION (US) 1986-07-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250081847-A1 POLYCYCLIC AROMATIC COMPOUND PAH, ALK, AOC2 ALOX5 3629/4885PTGS1 4634/4885ABCG2 71/4885
US-12473315-B2 Polycyclic aromatic compound PAH, ALK, AOC2 ALOX5 3629/4885PTGS1 4634/4885ABCG2 71/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.