Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEP1B | Q16820 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1994314 | 0.80 | MEP1B (0.41) | MEP1BKDM4EALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL3066742 | 0.78 | PTPN11 (0.32) | KDM4EALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL633227 | 0.77 | MEP1B (0.37) | MEP1BKDM4EALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL9873091 | 0.77 | KDM4E (0.43) | MEP1BKDM4EALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL20876054 | 0.77 | NQO1 (0.34) | — | |
| SCHEMBL23912421 | 0.74 | MEP1B (0.38) | MEP1BKDM4EALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL7960327 | 0.74 | MEP1B (0.41) | MEP1BMAPK1 | |
| SCHEMBL257259 | 0.74 | MEP1B (0.38) | MEP1BKDM4EALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL6885179 | 0.73 | KMT2A (0.38) | KDM4EALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL23780811 | 0.73 | MEP1B (0.41) | MEP1BKDM4EALDH1A1MAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4273147-A1 | SUBSTITUTED SPIROLACTAMS, SALTS THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES | Bayer Aktiengesellschaft (DE) | 2023-11-08 | — | — | EP | claimed |
| US-11834434-B2 | Substituted 2-heteroaryloxypyridines and salts thereof and their use as herbicidal agents | BAYER AKTIENGESELLSCHAFT (DE) | 2023-12-05 | — | — | US | disclosed |
| EP-4273147-A1 | SUBSTITUTED SPIROLACTAMS, SALTS THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES | Bayer Aktiengesellschaft (DE) | 2023-11-08 | — | — | EP | disclosed |
| CN-114507175-A | Novel inhibitors of hypnotic proteins alpha and beta | 维沃里翁治疗股份有限公司 | 2022-05-17 | — | — | CN | disclosed |
| CN-109195947-B | Novel inhibitors of hypnotic proteins alpha and beta | 维沃里翁治疗股份有限公司 | 2022-03-04 | — | — | CN | disclosed |
| EP-3445744-B1 | NOVEL INHIBITORS OF MEPRIN ALPHA AND BETA | VIVORYON THERAPEUTICS AG (DE) | 2021-10-06 | — | — | EP | disclosed |
| US-20210276974-A1 | SUBSTITUTED 2-HETEROARYLOXYPYRIDINES AND SALTS THEREOF AND THEIR USE AS HERBICIDAL AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 2021-09-09 | — | — | US | disclosed |
| US-20210198189-A1 | NOVEL INHIBITORS OF MEPRIN ALPHA AND BETA | VIVORYON THERAPEUTICS AG (DE) | 2021-07-01 | — | — | US | disclosed |
| US-10975019-B2 | Inhibitors of meprin α and β | VIVORYON THERAPEUTICS AG (DE) | 2021-04-13 | — | — | US | disclosed |
| US-20190127317-A1 | NOVEL INHIBITORS OF MEPRIN ALPHA AND BETA | VIVORYON THERAPEUTICS N.V (DE) | 2019-05-02 | — | — | US | disclosed |
| WO-1996009304-A1 | BENZOPYRANOPYRAZOLYL DERIVATIVES FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1996-03-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210276974-A1 | SUBSTITUTED 2-HETEROARYLOXYPYRIDINES AND SALTS THEREOF AND THEIR USE AS HERBICIDAL AGENTS | DDT, AGPS, GMDS | MEP1B 1434/4885KDM4E 1162/4885ALDH1A1 611/4885 |
| US-20190127317-A1 | NOVEL INHIBITORS OF MEPRIN ALPHA AND BETA | MEP1A, MEP1B, CAPRIN1 | MEP1B 2/4885KDM4E 3258/4885ALDH1A1 3469/4885 |
| US-11834434-B2 | Substituted 2-heteroaryloxypyridines and salts thereof and their use as herbicidal agents | DDT, AGPS, GMDS | MEP1B 1434/4885KDM4E 1162/4885ALDH1A1 611/4885 |
| US-20210198189-A1 | NOVEL INHIBITORS OF MEPRIN ALPHA AND BETA | MEP1A, MEP1B, CAPRIN1 | MEP1B 2/4885KDM4E 3258/4885ALDH1A1 3469/4885 |
| US-10975019-B2 | Inhibitors of meprin α and β | MEP1A, MEP1B, CAPRIN1 | MEP1B 2/4885KDM4E 2394/4885ALDH1A1 3070/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.