Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | TP53 | P04637 | 4/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | MPI | P34949 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12530911 | 0.85 | HSD17B10 (0.60) | KDM4EALOX15L3MBTL1LMNACYP1A2 | |
| SCHEMBL1787096 | 0.78 | KDM4E (0.68) | CACNA1BKDM4ETP53ALOX15ALOX12 | |
| SCHEMBL2237500 | 0.77 | BCHE (0.67) | CACNA1BKDM4ETP53ALOX15ALOX12 | |
| SCHEMBL19456453 | 0.76 | CACNA1B (0.47) | CACNA1BKDM4ETP53ALOX15ALOX12 | |
| Hydrochloric Acid SCHEMBL19437125 | 0.75 | BCHE (0.66) | CACNA1BKDM4ETP53ALOX15ALOX12 | |
| SCHEMBL6630089 | 0.75 | ALDH1A1 (0.46) | CACNA1BKDM4ETP53ALOX12L3MBTL1 | |
| SCHEMBL19437093 | 0.75 | KDM4E (0.54) | CACNA1BKDM4ETP53ALOX15ALOX12 | |
| SCHEMBL19456458 | 0.73 | CACNA1B (0.47) | CACNA1BKDM4ETP53ALOX15ALOX12 | |
| SCHEMBL7979681 | 0.71 | KDM4E (0.73) | CACNA1BKDM4ETP53ALOX15ALOX12 | |
| SCHEMBL31307138 | 0.70 | SMN1; SMN2 (0.52) | CACNA1BKDM4ETP53ALOX15ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996009291-A1 | 8-HYDROXYQUINOLINE DERIVATIVES USEFUL AS OXIDATION DYES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1996-03-28 | — | — | WO | disclosed |