Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | XDH | P47989 | 2/20 | 0.46 |
| ▸ | GSK3B | P49841 | 2/20 | 0.46 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27183319 | 0.85 | CYP19A1 (0.48) | CYP19A1TP53CYP3A4XDHGSK3B | |
| SCHEMBL15453093 | 0.81 | CYP19A1 (0.50) | CYP19A1TP53CYP3A4XDHGSK3B | |
| SCHEMBL11249388 | 0.80 | PBRM1 (0.38) | CYP19A1SMN1; SMN2CYP2C9CYP2C19POLB | |
| SCHEMBL2319151 | 0.78 | CYP19A1 (0.57) | CYP19A1TP53CYP3A4XDHGSK3B | |
| SCHEMBL18339272 | 0.77 | CYP19A1 (0.45) | CYP19A1TP53CYP3A4XDHGSK3B | |
| SCHEMBL14829729 | 0.77 | CYP19A1 (0.52) | CYP19A1TP53CYP3A4XDHGSK3B | |
| SCHEMBL27205452 | 0.77 | CYP19A1 (0.45) | CYP19A1TP53CYP3A4XDHGSK3B | |
| SCHEMBL7030025 | 0.76 | LMNA (0.48) | CYP19A1TP53CYP3A4GSK3BMAPT | |
| SCHEMBL382209 | 0.76 | TUBB4A (0.47) | CYP19A1TP53CYP3A4XDHGSK3B | |
| SCHEMBL5084443 | 0.75 | MEN1 (0.49) | CYP19A1CYP3A4CYP1A1CYP1A2CYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996031206-A2 | FLAVONES AND COUMARINS AS AGENTS FOR THE TREATMENT OF ATHEROSCLEROSIS | WARNER-LAMBERT COMPANY (US) | 1996-10-10 | — | — | WO | disclosed |