Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.82 |
| ▸ | CNR2 | P34972 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | GLA | P06280 | 4/20 | 0.52 |
| ▸ | GAA | P10253 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | NQO1 | P15559 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15398169 | 0.90 | GPR55 (1.00) | GPR55CNR2KDM4EALDH1A1GLA | |
| SCHEMBL28920340 | 0.78 | POLB (0.69) | GPR55KDM4EALDH1A1GLAGAA | |
| Anemarcoumarin A SCHEMBL774777 | 0.77 | POLB (0.77) | GPR55KDM4EALDH1A1GLAGAA | |
| SCHEMBL9529062 | 0.74 | — | — | |
| SCHEMBL29709847 | 0.72 | GPR55 (0.68) | GPR55KDM4EALDH1A1HPGDMAOB | |
| SCHEMBL19331106 | 0.72 | GPR55 (0.68) | GPR55KDM4EALDH1A1HPGDMAOB | |
| SCHEMBL1648127 | 0.71 | NQO1 (0.83) | ALDH1A1LMNANQO1TSHR | |
| SCHEMBL15082534 | 0.70 | HSD17B3 (0.51) | GPR55CNR2KDM4EALDH1A1GLA | |
| SCHEMBL15084994 | 0.70 | GPR55 (0.47) | GPR55CNR2KDM4EALDH1A1GLA | |
| SCHEMBL8963452 | 0.70 | KEAP1 (0.60) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996031206-A2 | FLAVONES AND COUMARINS AS AGENTS FOR THE TREATMENT OF ATHEROSCLEROSIS | WARNER-LAMBERT COMPANY (US) | 1996-10-10 | — | — | WO | claimed |
| WO-1996031206-A2 | FLAVONES AND COUMARINS AS AGENTS FOR THE TREATMENT OF ATHEROSCLEROSIS | WARNER-LAMBERT COMPANY (US) | 1996-10-10 | — | — | WO | disclosed |