Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 4/20 | 0.67 |
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.67 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.63 |
| ▸ | MAPT | P10636 | 6/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.63 |
| ▸ | HPGD | P15428 | 5/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.63 |
| ▸ | MEN1 | O00255 | 3/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | GLA | P06280 | 1/20 | 0.63 |
| ▸ | THRB | P10828 | 1/20 | 0.63 |
| ▸ | TERT | O14746 | 4/20 | 0.61 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.60 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8934503 | 0.89 | TERT (0.67) | ABCB1ABCG2ABCC1CYP3A4MAPT | |
| SCHEMBL29361605 | 0.80 | ABCG2 (1.00) | ABCB1ABCG2ABCC1CYP3A4MAPT | |
| SCHEMBL4650074 | 0.80 | ABCG2 (1.00) | ABCB1ABCG2ABCC1CYP3A4MAPT | |
| SCHEMBL13264829 | 0.80 | CYP1B1 (0.60) | ABCB1ABCG2ABCC1CYP3A4MAPT | |
| SCHEMBL29612043 | 0.79 | TERT (0.77) | ABCB1ABCG2ABCC1CYP3A4MAPT | |
| SCHEMBL988001 | 0.79 | TERT (0.77) | ABCB1ABCG2ABCC1CYP3A4MAPT | |
| 3',4'-Dimethoxyflavone SCHEMBL29623082 | 0.78 | CYP3A4 (1.00) | ABCB1ABCG2ABCC1CYP3A4MAPT | |
| 3',4'-Dimethoxyflavone SCHEMBL1675954 | 0.78 | CYP3A4 (1.00) | ABCB1ABCG2ABCC1CYP3A4MAPT | |
| 3',4'-Dimethoxyflavone SCHEMBL28140373 | 0.76 | CYP3A4 (0.97) | ABCB1ABCG2ABCC1CYP3A4MAPT | |
| SCHEMBL30626954 | 0.76 | CYP3A4 (0.76) | ABCB1ABCG2CYP3A4MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996031206-A2 | FLAVONES AND COUMARINS AS AGENTS FOR THE TREATMENT OF ATHEROSCLEROSIS | WARNER-LAMBERT COMPANY (US) | 1996-10-10 | — | — | WO | disclosed |