Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 6/20 | 1.00 |
| ▸ | ABCC1 | P33527 | 5/20 | 1.00 |
| ▸ | ABCB1 | P08183 | 5/20 | 1.00 |
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.80 |
| ▸ | CSNK2B | P67870 | 3/20 | 0.80 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.80 |
| ▸ | CYP1A1 | P04798 | 9/20 | 0.78 |
| ▸ | CYP1B1 | Q16678 | 9/20 | 0.78 |
| ▸ | CYP1A2 | P05177 | 7/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | HPGD | P15428 | 2/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | GLA | P06280 | 1/20 | 0.67 |
| ▸ | THRB | P10828 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29361605 | 1.00 | ABCG2 (1.00) | ABCG2ABCC1ABCB1CSNK2A2CSNK2B | |
| SCHEMBL14708633 | 0.89 | CSNK2A2 (1.00) | ABCG2ABCC1ABCB1CSNK2A2CSNK2B | |
| SCHEMBL4650874 | 0.85 | CYP1A1 (1.00) | ABCG2ABCC1ABCB1CSNK2A2CSNK2B | |
| SCHEMBL14696937 | 0.84 | ABCC1 (0.73) | ABCG2ABCC1ABCB1CSNK2A2CSNK2B | |
| SCHEMBL4649947 | 0.82 | CYP3A4 (0.76) | ABCG2ABCC1ABCB1CSNK2A2CSNK2B | |
| SCHEMBL988001 | 0.82 | TERT (0.77) | ABCG2ABCC1ABCB1CYP1A1CYP1B1 | |
| SCHEMBL29612043 | 0.82 | TERT (0.77) | ABCG2ABCC1ABCB1CYP1A1CYP1B1 | |
| SCHEMBL20594586 | 0.80 | CYP1A1 (0.78) | ABCG2ABCC1ABCB1CSNK2A2CSNK2B | |
| SCHEMBL29407618 | 0.80 | CYP1A1 (0.78) | ABCG2ABCC1ABCB1CSNK2A2CSNK2B | |
| 3',4'-Dimethoxyflavone SCHEMBL1675954 | 0.80 | CYP3A4 (1.00) | ABCG2ABCC1ABCB1CSNK2A2CSNK2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016168685-A1 | MODULATING THE ARYL HYDROCARBON RECEPTOR SYSTEM TO TREAT MAJOR DEPRESSIVE DISORDER | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2016-10-20 | — | — | WO | claimed |
| US-6872771-B1 | Tire with rubber containing flavone | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2005-03-29 | — | — | US | claimed |
| US-20250235422-A1 | DODECA-2,4,6,8,10-PENTAENOIC ACID COMPOSITIONS AND USES THEREOF | BIOMEDIT, INC. | 2025-07-24 | — | — | US | disclosed |
| US-20240293366-A1 | TOPICAL COMPOSITIONS AND METHODS FOR TREATING INFLAMMATORY SKIN DISEASES | AZORA THERAPEUTICS, INC. | 2024-09-05 | — | — | US | disclosed |
| EP-4252844-A2 | TOPICAL COMPOSITIONS AND METHODS FOR TREATING INFLAMMATORY SKIN DISEASES | AZORA THERAPEUTICS, INC. (US) | 2023-10-04 | — | — | EP | disclosed |
| EP-3955889-A1 | TOPICAL COMPOSITIONS AND METHODS FOR TREATING INFLAMMATORY SKIN DISEASES | AZORA THERAPEUTICS, INC. (US) | 2022-02-23 | — | — | EP | disclosed |
| US-20220023259-A1 | TOPICAL COMPOSITIONS AND METHODS FOR TREATING INFLAMMATORY SKIN DISEASES | AZORA THERAPEUTICS, INC. | 2022-01-27 | — | — | US | disclosed |
| US-11154533-B2 | Topical compositions and methods for treating inflammatory skin diseases | AZORA THERAPEUTICS, INC. (US) | 2021-10-26 | — | — | US | disclosed |
| US-20210186931-A1 | TOPICAL COMPOSITIONS AND METHODS FOR TREATING INFLAMMATORY SKIN DISEASES | AZORA THERAPEUTICS, INC. | 2021-06-24 | — | — | US | disclosed |
| WO-2020214855-A1 | TOPICAL COMPOSITIONS AND METHODS FOR TREATING INFLAMMATORY SKIN DISEASES | AZORA THERAPEUTICS, INC. (US) | 2020-10-22 | — | — | WO | disclosed |
| EP-2730431-B1 | Rubber composition and tire with rubber containing flavone | GOODYEAR TIRE & RUBBER (US) | 2017-06-28 | — | — | EP | disclosed |
| WO-2016168685-A1 | MODULATING THE ARYL HYDROCARBON RECEPTOR SYSTEM TO TREAT MAJOR DEPRESSIVE DISORDER | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2016-10-20 | — | — | WO | disclosed |
| US-20140135433-A1 | TIRE WITH RUBBER CONTAINING FLAVONE | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2014-05-15 | — | — | US | disclosed |
| EP-2730431-A1 | Rubber composition and tire with rubber containing flavone | The Goodyear Tire & Rubber Company (US) | 2014-05-14 | — | — | EP | disclosed |
| EP-1391327-B1 | Tire with rubber containing flavone | GOODYEAR TIRE & RUBBER (US) | 2008-09-03 | — | — | EP | disclosed |
| US-6872771-B1 | Tire with rubber containing flavone | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2005-03-29 | — | — | US | disclosed |
| EP-1391327-A1 | Tire with rubber containing flavone | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2004-02-25 | — | — | EP | disclosed |
| WO-2003057210-A1 | COMPOSITIONS AND METHODS FOR INCREASING CELL PROLIFERATION COMPRISING A FLAVONOID | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2003-07-17 | — | — | WO | disclosed |
| US-20030125264-A1 | Methods For Treating Wounds | KIMBERLY-CLARK WORLDWIDE, INC. | 2003-07-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210186931-A1 | TOPICAL COMPOSITIONS AND METHODS FOR TREATING INFLAMMATORY SKIN DISEASES | AHR, ARNT, TLR8 | ABCG2 356/4885ABCC1 1453/4885ABCB1 705/4885 |
| US-20250235422-A1 | DODECA-2,4,6,8,10-PENTAENOIC ACID COMPOSITIONS AND USES THEREOF | CUTA, ALOX5AP, DAGLA | ABCG2 3812/4885ABCC1 3506/4885ABCB1 3197/4885 |
| US-11154533-B2 | Topical compositions and methods for treating inflammatory skin diseases | AHR, ARNT, TLR8 | ABCG2 356/4885ABCC1 1453/4885ABCB1 705/4885 |
| US-20240293366-A1 | TOPICAL COMPOSITIONS AND METHODS FOR TREATING INFLAMMATORY SKIN DISEASES | AHR, ARNT, TLR8 | ABCG2 356/4885ABCC1 1453/4885ABCB1 705/4885 |
| US-20030125264-A1 | Methods For Treating Wounds | FGF2, MMP1, FIBP | ABCG2 3752/4885ABCC1 4497/4885ABCB1 2498/4885 |
| US-20220023259-A1 | TOPICAL COMPOSITIONS AND METHODS FOR TREATING INFLAMMATORY SKIN DISEASES | AHR, ARNT, TLR8 | ABCG2 356/4885ABCC1 1453/4885ABCB1 705/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.