Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 3/20 | 0.67 |
| ▸ | CSNK2A2 | P19784 | 5/20 | 0.56 |
| ▸ | CSNK2B | P67870 | 5/20 | 0.56 |
| ▸ | CSNK2A1 | P68400 | 5/20 | 0.56 |
| ▸ | PTGES | O14684 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.54 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.54 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8934531 | 0.89 | ABCB1 (0.67) | TERTCSNK2A2CSNK2BCSNK2A1CYP3A4 | |
| SCHEMBL22230879 | 0.85 | TERT (0.69) | TERTCSNK2A2CSNK2BCSNK2A1PTGES | |
| SCHEMBL6612048 | 0.82 | TERT (0.88) | TERTCSNK2A2CSNK2BCSNK2A1PTGES | |
| SCHEMBL6614126 | 0.81 | TERT (1.00) | TERTCSNK2A2CSNK2BCSNK2A1CYP3A4 | |
| SCHEMBL6613755 | 0.81 | TERT (0.77) | TERTCSNK2A2CSNK2BCSNK2A1CYP3A4 | |
| SCHEMBL6614365 | 0.80 | TERT (0.80) | TERTCSNK2A2CSNK2BCSNK2A1CYP3A4 | |
| SCHEMBL5320080 | 0.79 | KDM4E (0.81) | TERTCSNK2A2CSNK2BCSNK2A1PTGES | |
| SCHEMBL6129133 | 0.77 | TUBB4A (0.71) | TERTCYP3A4MAPTALDH1A1MAPK1 | |
| SCHEMBL13264829 | 0.77 | CYP1B1 (0.60) | TERTCYP3A4MAPTHPGDCYP2C9 | |
| SCHEMBL6613454 | 0.76 | TERT (1.00) | TERTCSNK2A2CSNK2BCSNK2A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996031206-A2 | FLAVONES AND COUMARINS AS AGENTS FOR THE TREATMENT OF ATHEROSCLEROSIS | WARNER-LAMBERT COMPANY (US) | 1996-10-10 | — | — | WO | claimed |
| WO-1996031206-A2 | FLAVONES AND COUMARINS AS AGENTS FOR THE TREATMENT OF ATHEROSCLEROSIS | WARNER-LAMBERT COMPANY (US) | 1996-10-10 | — | — | WO | disclosed |