Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.38 |
| ▸ | USP7 | Q93009 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8934510 | 0.85 | NPC1 (0.41) | MAOAMAOBCYP19A1NR1H4POLB | |
| SCHEMBL9377374 | 0.80 | USP7 (0.41) | POLBTP53RXFP1DNMT1CYP11B1 | |
| SCHEMBL9376799 | 0.78 | DNMT1 (0.35) | NR1H4POLBTP53RXFP1DNMT1 | |
| SCHEMBL9375099 | 0.76 | TLR8 (0.36) | POLBTP53RXFP1DNMT1CYP11B1 | |
| Hydrochloric Acid SCHEMBL9375280 | 0.76 | RAB9A (0.49) | TP53ALDH1A1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL9380562 | 0.76 | NPC1 (0.39) | POLBTP53RXFP1DNMT1CYP11B1 | |
| Hydrochloric Acid SCHEMBL9376404 | 0.76 | NPC1 (0.38) | POLBTP53RXFP1DNMT1CYP11B1 | |
| SCHEMBL9376144 | 0.74 | MAPT (0.38) | POLBTP53RXFP1USP7KDM4E | |
| SCHEMBL9375701 | 0.73 | DNMT1 (0.35) | NR1H4POLBTP53RXFP1DNMT1 | |
| SCHEMBL9378049 | 0.73 | MAPT (0.38) | POLBTP53RXFP1DNMT1CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996030350-A1 | AMIDINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-10-03 | — | — | WO | disclosed |