Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNMT1 | P26358 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | COMT | P21964 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 3/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.32 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9376180 | 0.76 | TYMS (0.37) | — | |
| SCHEMBL8934510 | 0.76 | NPC1 (0.41) | DNMT1ALDH1A1KDM4ECYP11B1CYP11B2 | |
| SCHEMBL10651267 | 0.76 | CYP11B1 (0.45) | ALDH1A1KDM4ECYP11B1CYP11B2MAPT | |
| Hydrochloric Acid SCHEMBL9376635 | 0.76 | TYMS (0.37) | ALDH1A1KDM4EMEN1NPC1RAB9A | |
| SCHEMBL9375099 | 0.75 | TLR8 (0.36) | DNMT1ALDH1A1KDM4ECYP11B1CYP11B2 | |
| SCHEMBL9378049 | 0.74 | MAPT (0.38) | DNMT1ALDH1A1KDM4ECYP11B1CYP11B2 | |
| SCHEMBL9377374 | 0.74 | USP7 (0.41) | DNMT1ALDH1A1KDM4ECYP11B1CYP11B2 | |
| SCHEMBL8934543 | 0.73 | MAOA (0.43) | DNMT1ALDH1A1KDM4ECYP11B1CYP11B2 | |
| Potassium Ion SCHEMBL9376909 | 0.73 | MAPT (0.36) | DNMT1ALDH1A1KDM4ECYP11B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL9375280 | 0.73 | RAB9A (0.49) | ALDH1A1MAPTTP53NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0356234-B1 | New Benzazole compounds, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1994-05-11 | — | — | EP | disclosed |
| US-5047411-A | Antiulcer Agents, H2-Receptor Antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-09-10 | — | — | US | disclosed |
| EP-0356234-A2 | New Benzazole compounds, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-02-28 | — | — | EP | disclosed |