Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.56 |
| ▸ | HPGD | P15428 | 10/20 | 0.56 |
| ▸ | GAA | P10253 | 6/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.56 |
| ▸ | GLA | P06280 | 5/20 | 0.56 |
| ▸ | CASP1 | P29466 | 5/20 | 0.56 |
| ▸ | CASP7 | P55210 | 5/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13453098 | 0.86 | ALDH1A1 (0.51) | ALDH1A1KDM4EHPGDGAAHSD17B10 | |
| Dimefline SCHEMBL30539856 | 0.83 | ALDH1A1 (0.50) | ALDH1A1KDM4EHPGDGAAHSD17B10 | |
| Dimefline SCHEMBL668130 | 0.83 | ALDH1A1 (0.50) | ALDH1A1KDM4EHPGDGAAHSD17B10 | |
| SCHEMBL18222875 | 0.83 | KDM4E (0.67) | ALDH1A1KDM4EHPGDGAAHSD17B10 | |
| Dimefline SCHEMBL121889 | 0.82 | ALDH1A1 (0.49) | ALDH1A1KDM4EHPGDGAAHSD17B10 | |
| SCHEMBL12325677 | 0.77 | ALOX15 (0.64) | ALDH1A1KDM4EHPGDGAAHSD17B10 | |
| SCHEMBL8877681 | 0.76 | ALDH1A1 (0.56) | ALDH1A1KDM4EHPGDGAAHSD17B10 | |
| SCHEMBL14317878 | 0.75 | SHBG (0.73) | ALDH1A1KDM4EHPGDGAAHSD17B10 | |
| SCHEMBL14266215 | 0.73 | CYP1A2 (0.45) | ALDH1A1KDM4EHPGDGAAHSD17B10 | |
| SCHEMBL22266149 | 0.72 | GAA (0.58) | ALDH1A1KDM4EHPGDGAAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996031206-A2 | FLAVONES AND COUMARINS AS AGENTS FOR THE TREATMENT OF ATHEROSCLEROSIS | WARNER-LAMBERT COMPANY (US) | 1996-10-10 | — | — | WO | claimed |
| WO-1996031206-A2 | FLAVONES AND COUMARINS AS AGENTS FOR THE TREATMENT OF ATHEROSCLEROSIS | WARNER-LAMBERT COMPANY (US) | 1996-10-10 | — | — | WO | disclosed |