Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 16/20 | 1.00 |
| ▸ | DRD2 | P14416 | 11/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | ACHE | P22303 | 1/20 | 0.55 |
| ▸ | DRD3 | P35462 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8431223 | 0.91 | DRD4 (1.00) | DRD4DRD2KDM4EUSP2ALDH1A1 | |
| SCHEMBL8431350 | 0.88 | DRD4 (1.00) | DRD4DRD2DRD3 | |
| SCHEMBL8431699 | 0.87 | DRD4 (1.00) | DRD4DRD2KDM4EALDH1A1MAPT | |
| SCHEMBL8433471 | 0.83 | DRD4 (1.00) | DRD4DRD2KDM4EALDH1A1 | |
| SCHEMBL8433608 | 0.81 | DRD4 (0.80) | DRD4DRD2DRD3 | |
| SCHEMBL8435196 | 0.80 | DRD4 (1.00) | DRD4DRD2 | |
| SCHEMBL11830305 | 0.80 | KMT2A (0.76) | DRD4DRD2ACHEDRD3 | |
| SCHEMBL8431572 | 0.79 | DRD4 (1.00) | DRD4DRD2DRD3 | |
| SCHEMBL8520441 | 0.79 | DRD4 (0.77) | DRD4DRD2DRD3 | |
| SCHEMBL8431470 | 0.79 | DRD4 (1.00) | DRD4DRD2KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996031206-A2 | FLAVONES AND COUMARINS AS AGENTS FOR THE TREATMENT OF ATHEROSCLEROSIS | WARNER-LAMBERT COMPANY (US) | 1996-10-10 | — | — | WO | claimed |
| WO-1996031206-A2 | FLAVONES AND COUMARINS AS AGENTS FOR THE TREATMENT OF ATHEROSCLEROSIS | WARNER-LAMBERT COMPANY (US) | 1996-10-10 | — | — | WO | disclosed |