SCHEMBL8934570

SCHEMBL8934570

Oc1c(O)c2cc(Br)ccc2c2ccc(Br)cc12

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 3/20 0.46
ESR2 Q92731 2/20 0.42
PIM1 P11309 2/20 0.41
ERN1 O75460 2/20 0.39
HPGD P15428 2/20 0.39
CES2 O00748 1/20 0.39
GALR3 O60755 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2C9 P11712 1/20 0.39
CASP1 P29466 1/20 0.39
CYP2C19 P33261 1/20 0.39
CYP3A4 P08684 1/20 0.39
TSHR P16473 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
LMNA P02545 1/20 0.39
MAPT P10636 1/20 0.39
HTT P42858 1/20 0.39
ATM Q13315 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30906876 0.89 ALOX15 (0.46) ALOX15ESR2PIM1ERN1HPGD
SCHEMBL11054327 0.82 MEN1 (0.46) ALOX15PIM1CES2GALR3MEN1
SCHEMBL29566170 0.82 MEN1 (0.46) ALOX15PIM1CES2GALR3MEN1
SCHEMBL16158369 0.82 CYP2A6 (0.47) ALOX15ESR2PIM1TDP1MEN1
SCHEMBL11791238 0.80 ALOX15 (0.44) ALOX15PIM1ERN1HPGDCES2
Biphenyl SCHEMBL3247454 0.77 CRHBP (0.52) MEN1KMT2AATMSMN1; SMN2AR
SCHEMBL13616030 0.77 BCL2 (0.45) ALOX15ESR2PIM1TDP1MEN1
SCHEMBL25411614 0.75 MEN1 (0.45) ALOX15ESR2CES2GALR3CYP3A4
Biphenyl SCHEMBL3244538 0.75 CRHBP (0.50) MEN1KMT2AATMSMN1; SMN2AR
SCHEMBL9656401 0.75 CA12 (0.42) ALOX15HPGDCES2GALR3TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-8134193-A None JP disclosed
CN-112679732-B Luminescent polymer and metal-free catalyst polymerization method and application thereof 华南理工大学 2021-10-26 CN disclosed
CN-112679732-A Luminescent polymer and metal-free catalyst polymerization method and application thereof 华南理工大学 2021-04-20 CN disclosed
CN-103254044-B 2,7-bis-bromo-9,10 replacements-phenanthrene derivative Henan Academy of SciencesChemistry Institute Co., Ltd. (CN) 2015-08-26 CN disclosed
CN-103724283-A 2,7-alkyl substituted phenanthro [9,10-b] pyrazine derivative monomer, preparation method of 2,7-alkyl substituted phenanthro [9,10-b] pyrazine derivative monomer and polymer UNIV SOUTH CHINA TECH 2014-04-16 CN disclosed
CN-102775279-B 2,7-dibromo-9-hydroxyl phenanthrene derivatives and preparation method thereof INST CHEMISTRY CO LTD HENAN ACADEMY OF SCIENCES 2014-03-05 CN disclosed
CN-103254044-A 2,7-dibromide-9,10 substituted-phenanthrene derivatives INST CHEMISTRY CO LTD HENAN ACADEMY OF SCIENCES 2013-08-21 CN disclosed
CN-102775279-A 2,7-dibromo-9-hydroxyl phenanthrene derivatives and preparation method thereof INST CHEMISTRY CO LTD HENAN ACADEMY OF SCIENCES 2012-11-14 CN disclosed
JP-H08134193-A NEW POLYESTER AND ITS PRODUCTION AGENCY OF IND SCIENCE & TECHNOL 1996-05-28 JP disclosed