Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.50 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.43 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.43 |
| ▸ | CSF1R | P07333 | 1/20 | 0.43 |
| ▸ | FER | P16591 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | MARK3 | P27448 | 1/20 | 0.43 |
| ▸ | FLT4 | P35916 | 1/20 | 0.43 |
| ▸ | FLT3 | P36888 | 1/20 | 0.43 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.43 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.43 |
| ▸ | CLK2 | P49760 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Biphenyl SCHEMBL3247454 | 0.98 | CRHBP (0.52) | CRHBPCRHR2ALDH1A1MAPK1RXFP1 | |
| SCHEMBL29566170 | 0.92 | MEN1 (0.46) | ALDH1A1RXFP1MEN1KMT2AAR | |
| SCHEMBL11054327 | 0.92 | MEN1 (0.46) | ALDH1A1RXFP1MEN1KMT2AAR | |
| SCHEMBL9971889 | 0.79 | ALOX5 (0.54) | CRHBPCRHR2ALDH1A1MEN1KMT2A | |
| SCHEMBL17343994 | 0.78 | ALDH1A1 (0.56) | CRHBPCRHR2ALDH1A1MAPK1RXFP1 | |
| SCHEMBL16076432 | 0.78 | ALDH1A1 (0.56) | CRHBPCRHR2ALDH1A1MAPK1RXFP1 | |
| SCHEMBL25411614 | 0.76 | MEN1 (0.45) | MAPK1RXFP1MEN1KMT2AAR | |
| SCHEMBL28924402 | 0.76 | ALDH1A1 (0.54) | ALDH1A1MAPK1RXFP1MEN1KMT2A | |
| SCHEMBL12791336 | 0.76 | ALDH1A1 (0.54) | ALDH1A1MAPK1RXFP1MEN1KMT2A | |
| SCHEMBL8934570 | 0.75 | ALOX15 (0.46) | RXFP1MEN1KMT2APRKD3MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1645552-B1 | Electroluminescent devices made with double-spiro organic compounds | LG CHEMICAL LTD (KR) | 2010-05-05 | — | — | EP | disclosed |
| EP-1294823-B1 | DOUBLE-SPIRO ORGANIC COMPOUNDS AND ELECTROLUMINESCENT DEVICES | LG CHEMICAL LTD (KR) | 2006-12-13 | — | — | EP | disclosed |
| EP-1645552-A1 | Double-spiro organic compounds and electroluminescent devices | LG Chem, Ltd. (KR) | 2006-04-12 | — | — | EP | disclosed |
| US-6998487-B2 | Double-spiro organic compounds and organic electroluminescent devices using the same | LG CHEM, LTD. (KR) | 2006-02-14 | — | — | US | disclosed |
| US-6984462-B2 | Organic electroluminescent devices using double-spiro organic compounds | LG CHEM, LTD. (KR) | 2006-01-10 | — | — | US | disclosed |
| US-20040170863-A1 | Organic electroluminescent devices using double-spiro organic compounds | LG CHEM, LTD. (KR) | 2004-09-02 | — | — | US | disclosed |
| US-20040023060-A1 | Double-spiro organic compounds and organic electroluminescent devices using the same | LG CHEM, LTD. (KR) | 2004-02-05 | — | — | US | disclosed |
| EP-1294823-A1 | DOUBLE-SPIRO ORGANIC COMPOUNDS AND ELECTROLUMINESCENT DEVICES | LG Chem, Ltd. (KR) | 2003-03-26 | — | — | EP | disclosed |
| WO-2002088274-A1 | DOUBLE-SPIRO ORGANIC COMPOUNDS AND ELECTROLUMINESCENT DEVICES | LG CHEM, LTD. (KR) | 2002-11-07 | — | — | WO | disclosed |