Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.67 |
| ▸ | RAB9A | P51151 | 8/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.67 |
| ▸ | NPC1 | O15118 | 7/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.67 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | HPGD | P15428 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | NCOA1 | Q15788 | 2/20 | 0.57 |
| ▸ | GLA | P06280 | 1/20 | 0.57 |
| ▸ | PPARG | P37231 | 1/20 | 0.57 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | GAPDH | P04406 | 2/20 | 0.56 |
| ▸ | ESR1 | P03372 | 1/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 3/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13757025 | 0.84 | ALDH1A1 (0.75) | ALDH1A1RAB9ASMN1; SMN2NPC1KDM4E | |
| SCHEMBL8447062 | 0.80 | ALDH1A1 (0.69) | ALDH1A1RAB9ASMN1; SMN2NPC1KDM4E | |
| SCHEMBL8934577 | 0.78 | ALDH1A1 (0.68) | ALDH1A1RAB9ASMN1; SMN2NPC1KDM4E | |
| SCHEMBL13757026 | 0.78 | ALDH1A1 (0.67) | ALDH1A1RAB9ASMN1; SMN2NPC1KDM4E | |
| SCHEMBL19003439 | 0.78 | ALDH1A1 (0.69) | ALDH1A1RAB9ASMN1; SMN2NPC1KDM4E | |
| SCHEMBL14880355 | 0.75 | ALDH1A1 (0.68) | ALDH1A1RAB9ASMN1; SMN2NPC1KDM4E | |
| SCHEMBL12010984 | 0.75 | MAOB (0.63) | ALDH1A1RAB9ASMN1; SMN2NPC1KDM4E | |
| SCHEMBL15216064 | 0.75 | ALDH1A1 (0.69) | ALDH1A1RAB9ASMN1; SMN2NPC1KDM4E | |
| SCHEMBL14880142 | 0.75 | ALDH1A1 (0.69) | ALDH1A1RAB9ASMN1; SMN2NPC1KDM4E | |
| SCHEMBL12387899 | 0.75 | ALDH1A1 (0.69) | ALDH1A1RAB9ASMN1; SMN2NPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996031206-A2 | FLAVONES AND COUMARINS AS AGENTS FOR THE TREATMENT OF ATHEROSCLEROSIS | WARNER-LAMBERT COMPANY (US) | 1996-10-10 | — | — | WO | disclosed |