Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.69 |
| ▸ | MAOB | P27338 | 4/20 | 0.69 |
| ▸ | RAB9A | P51151 | 3/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.69 |
| ▸ | HPGD | P15428 | 3/20 | 0.66 |
| ▸ | NPC1 | O15118 | 2/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.66 |
| ▸ | GAPDH | P04406 | 2/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.66 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.66 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.66 |
| ▸ | ESR1 | P03372 | 1/20 | 0.66 |
| ▸ | GAA | P10253 | 1/20 | 0.66 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | PGR | P06401 | 4/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.51 |
| ▸ | APP | P05067 | 1/20 | 0.50 |
| ▸ | TNKS | O95271 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL194955 | 0.84 | NPC1 (0.62) | ALDH1A1MAOBRAB9AKDM4EHPGD | |
| Coumarin SCHEMBL28308230 | 0.83 | RAB9A (0.62) | ALDH1A1MAOBRAB9AKDM4EHPGD | |
| SCHEMBL14389070 | 0.83 | MAOB (0.75) | ALDH1A1MAOBRAB9AKDM4EHPGD | |
| SCHEMBL12611207 | 0.82 | MIF (0.62) | MAOBESR2MAPTPGRADORA3 | |
| SCHEMBL3136457 | 0.82 | PGR (0.57) | ALDH1A1MAOBRAB9AKDM4EHPGD | |
| SCHEMBL30356319 | 0.82 | RAB9A (1.00) | ALDH1A1MAOBRAB9AKDM4EHPGD | |
| SCHEMBL177366 | 0.82 | RAB9A (1.00) | ALDH1A1MAOBRAB9AKDM4EHPGD | |
| SCHEMBL4985529 | 0.81 | MAOB (0.55) | MAOBKDM4EMAPTPGRADORA3 | |
| SCHEMBL4988885 | 0.81 | MAOB (0.55) | MAOBKDM4ENPC1GAPDHPGR | |
| SCHEMBL13869330 | 0.80 | CYP19A1 (0.73) | ALDH1A1MAOBRAB9AKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170176469-A1 | Molecular Probes for Detecting Lipids | CASE WESTERN UNIVERSITY | 2017-06-22 | — | — | US | disclosed |
| US-20170176469-A1 | Molecular Probes for Detecting Lipids | CASE WESTERN UNIVERSITY | 2017-06-22 | — | — | US | disclosed |
| US-20140079635-A1 | MOLECULAR PROBES FOR DETECTING LIPID COMPOSITION | CASE WESTERN RESERVE UNIVERSITY (US) | 2014-03-20 | — | — | US | disclosed |
| US-20140079635-A1 | MOLECULAR PROBES FOR DETECTING LIPID COMPOSITION | CASE WESTERN RESERVE UNIVERSITY (US) | 2014-03-20 | — | — | US | disclosed |
| WO-2013126898-A1 | MOLECULAR PROBES FOR DETECTING LIPIDS | CASE WESTERN RESERVE UNIVERSITY (US) | 2013-08-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140079635-A1 | MOLECULAR PROBES FOR DETECTING LIPID COMPOSITION | MAG, FABP7, PMP22 | ALDH1A1 2831/4885MAOB 3390/4885RAB9A 3500/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.