Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | NPY1R | P25929 | 11/20 | 0.46 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8934491 | 0.85 | POLB (0.48) | POLBNPY1RAOC3SIGMAR1 | |
| SCHEMBL8934627 | 0.80 | AOC3 (0.53) | POLBNPY1RAOC3 | |
| SCHEMBL8934519 | 0.75 | POLB (0.54) | POLBNPY1RAOC3HPGD | |
| SCHEMBL9629092 | 0.73 | POLB (0.55) | POLBNPY1RAOC3HPGD | |
| SCHEMBL8722548 | 0.73 | KCNH2 (0.50) | POLBKCNH2KCNJ1SIGMAR1SLC6A4 | |
| SCHEMBL9629111 | 0.72 | POLB (0.54) | POLBNPY1RAOC3HPGD | |
| SCHEMBL9628458 | 0.71 | POLB (0.53) | POLBNPY1RAOC3HPGD | |
| SCHEMBL9628041 | 0.71 | POLB (0.53) | POLBNPY1RAOC3HPGD | |
| SCHEMBL9628556 | 0.71 | POLB (0.53) | POLBNPY1RAOC3HPGD | |
| SCHEMBL8934522 | 0.68 | POLB (0.52) | POLBNPY1RAOC3HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996030350-A1 | AMIDINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-10-03 | — | — | WO | disclosed |