Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NPY1R | P25929 | 4/20 | 0.45 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.43 |
| ▸ | NCF1 | P14598 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8934644 | 0.84 | POLB (0.52) | POLBHPGDALDH1A1 | |
| SCHEMBL8934491 | 0.75 | POLB (0.48) | POLBNPY1RAOC3 | |
| SCHEMBL9629092 | 0.72 | POLB (0.55) | POLBHPGDALDH1A1KMT2ANPY1R | |
| SCHEMBL7354403 | 0.71 | POLB (1.00) | POLBHPGDALDH1A1KMT2ANPY1R | |
| SCHEMBL8934627 | 0.71 | AOC3 (0.53) | POLBHRH3NPY1RAOC3 | |
| SCHEMBL9628041 | 0.70 | POLB (0.53) | POLBHPGDALDH1A1KMT2ANPY1R | |
| SCHEMBL9628556 | 0.70 | POLB (0.53) | POLBHPGDALDH1A1KMT2ANPY1R | |
| SCHEMBL29642975 | 0.70 | HRH3 (0.64) | POLBALDH1A1HRH3HRH4KDM4E | |
| SCHEMBL11201497 | 0.70 | HRH3 (0.94) | POLBALDH1A1HRH3HRH4KDM4E | |
| SCHEMBL25188622 | 0.68 | NCF1 (0.57) | POLBALDH1A1HRH3HRH4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996030350-A1 | AMIDINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-10-03 | — | — | WO | disclosed |