Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | CES1 | P23141 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8934676 | 0.81 | MAPT (0.41) | MAPTNPSR1LMNASMN1; SMN2XBP1 | |
| SCHEMBL8934708 | 0.77 | TDP1 (0.42) | TSHRMAPTNPSR1LMNASMN1; SMN2 | |
| SCHEMBL14642986 | 0.75 | MAPT (0.44) | TSHRMAPTNPSR1LMNASMN1; SMN2 | |
| SCHEMBL8934663 | 0.73 | MAPT (0.44) | TSHRMAPTNPSR1LMNASMN1; SMN2 | |
| SCHEMBL8934698 | 0.73 | ATM (0.33) | TSHRMAPTNPSR1LMNASMN1; SMN2 | |
| SCHEMBL8934666 | 0.73 | MAPK1 (0.47) | TSHRMAPTNPSR1LMNASMN1; SMN2 | |
| SCHEMBL8934712 | 0.69 | ALDH1A1 (0.46) | TSHRMAPTNPSR1LMNASMN1; SMN2 | |
| SCHEMBL693987 | 0.69 | SMN1; SMN2 (0.50) | TSHRMAPTNPSR1LMNASMN1; SMN2 | |
| SCHEMBL11798431 | 0.68 | MAPT (0.45) | TSHRMAPTNPSR1LMNASMN1; SMN2 | |
| SCHEMBL26712 | 0.68 | TSHR (0.52) | TSHRMAPTLMNAATMRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996030415-A1 | ALKOXY ALLYL (DI)PEROXIDE CHAIN TRANSFER AGENTS | AKZO NOBEL N.V. (NL) | 1996-10-03 | — | — | WO | disclosed |