SCHEMBL693987

SCHEMBL693987

C=C(c1ccccc1)C(C)C

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.50
LMNA P02545 3/20 0.50
NPSR1 Q6W5P4 3/20 0.50
MAPT P10636 2/20 0.50
XBP1 P17861 1/20 0.50
ATM Q13315 1/20 0.50
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
ALDH1A1 P00352 4/20 0.41
HPGD P15428 2/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
HTT P42858 1/20 0.38
RAB9A P51151 1/20 0.38
ELANE P08246 1/20 0.38
CES2 O00748 3/20 0.38
CES1 P23141 3/20 0.38
TSHR P16473 2/20 0.38
DAO P14920 1/20 0.38
NAPRT Q6XQN6 1/20 0.38
HTR2A P28223 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrogen Sulfide SCHEMBL29028321 0.97 SMN1; SMN2 (0.48) SMN1; SMN2LMNANPSR1MAPTXBP1
SCHEMBL8461563 0.86 MAPT (0.35) SMN1; SMN2LMNANPSR1MAPTXBP1
SCHEMBL3731992 0.82 LMNA (0.48) SMN1; SMN2LMNANPSR1MAPTXBP1
SCHEMBL8464546 0.82 KMT2A (0.39) SMN1; SMN2LMNANPSR1MAPTXBP1
SCHEMBL4021295 0.80 LMNA (0.47) SMN1; SMN2LMNANPSR1MAPTXBP1
SCHEMBL4662816 0.80 LMNA (0.47) SMN1; SMN2LMNANPSR1MAPTXBP1
SCHEMBL7854232 0.80 SMN1; SMN2 (0.52) SMN1; SMN2LMNANPSR1MAPTXBP1
SCHEMBL830415 0.80 SMN1; SMN2 (0.47) SMN1; SMN2LMNANPSR1MAPTXBP1
SCHEMBL8285027 0.78 LMNA (0.45) SMN1; SMN2LMNANPSR1MAPTXBP1
SCHEMBL14530150 0.78 TSHR (0.55) SMN1; SMN2KMT2AALDH1A1HPGDCES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 276 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119039195-A Preparation method of beta-thiocyanate alcohol derivative 山东省分析测试中心 2024-11-29 CN claimed
CN-108144589-B Resin, preparation method thereof and method for treating wastewater by using resin 万华化学集团股份有限公司 2020-08-28 CN claimed
US-9296832-B2 Anionic polymerization methods for producing functionalized polymers BRIDGESTONE CORPORATION (JP) 2016-03-29 US claimed
EP-2504365-B1 ANIONIC POLYMERIZATION METHODS FOR PRODUCING FUNCTIONALIZED POLYMERS BRIDGESTONE CORP (JP) 2014-05-14 EP claimed
US-20130030133-A1 ANIONIC POLYMERIZATION METHODS FOR PRODUCING FUNCTIONALIZED POLYMERS BRIDGESTONE CORPORATION (JP) 2013-01-31 US claimed
US-5191040-A Peroxide catalyst IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1993-03-02 US claimed
US-4794145-A REACTING WITH ALKYL SUBSTITUTED STYRENE, THEN MONOMER THE DOW CHEMICAL COMPANY (US) 1988-12-27 US claimed
EP-0047109-B1 RHODANINE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND ALDOSE REDUCTASE INHIBITOR CONTAINING THE RHODANINE DERIVATIVES AS ACTIVE INGREDIENT ONO PHARMACEUTICAL CO., LTD. (JP) 1985-01-02 EP claimed
US-4438222-A ALPHA-ALKYLSTYRENE COPOLYMERS KANEGAFUCHI CHEMICAL INDUSTRY CO., LTD. (JP) 1984-03-20 US claimed
US-4327191-A THEN AMINATING RHONE-POULENC INDUSTRIES (FR) 1982-04-27 US claimed
EP-0047109-A1 Rhodanine derivatives, process for their preparation, and aldose reductase inhibitor containing the rhodanine derivatives as active ingredient ONO PHARMACEUTICAL CO., LTD. (JP) 1982-03-10 EP claimed
CN-119039195-A Preparation method of beta-thiocyanate alcohol derivative 山东省分析测试中心 2024-11-29 CN disclosed
CN-112867705-B Opioid receptor modulators and products and methods related thereto 埃皮欧黛公司 2024-08-20 CN disclosed
EP-3774722-B1 OPIOID RECEPTOR MODULATORS AND PRODUCTS AND METHODS RELATED THERETO EPIODYNE INC (US) 2024-07-24 EP disclosed
CN-118359525-A Se-deuterated methyl-arylsulfonyl selenate compound and synthetic method and application thereof 浙江工业大学 2024-07-19 CN disclosed
US-4369298-A Novel cured resin, process for production thereof, and lens composed of said resin from bis(alkyleneoxyphenyl)-diacrylate, bis(alkyleneoxyphenyl)diallyl ether, bis(alkyleneoxyphenyl)diallyl carbonate monomers TOKUYAMA SODA KABUSHIKI KAISHA (JP) 1983-01-18 US disclosed
EP-0048145-A1 Heat resistant expandable plastic particles and moulded products made therefrom KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1982-03-24 EP disclosed
EP-0047109-A1 Rhodanine derivatives, process for their preparation, and aldose reductase inhibitor containing the rhodanine derivatives as active ingredient ONO PHARMACEUTICAL CO., LTD. (JP) 1982-03-10 EP disclosed
US-4147550-A Photographic silver halide element with a layer of sulfonated polymer EASTMAN KODAK COMPANY (US) 1979-04-03 US disclosed
US-3946081-A OXIDATION CATALYSTS, GROUP V, VI, OR VII OXIDES BAYER AKTIENGESELLSCHAFT (DT) 1976-03-23 US disclosed