Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.61 |
| ▸ | CA12 | O43570 | 2/20 | 0.53 |
| ▸ | CA1 | P00915 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | CA3 | P07451 | 2/20 | 0.53 |
| ▸ | CA4 | P22748 | 2/20 | 0.53 |
| ▸ | CA6 | P23280 | 2/20 | 0.53 |
| ▸ | CA5A | P35218 | 2/20 | 0.53 |
| ▸ | CA7 | P43166 | 2/20 | 0.53 |
| ▸ | CA9 | Q16790 | 2/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.53 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | SELL | P14151 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | SELP | P16109 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14620895 | 0.92 | PTGS2 (0.59) | PTGS2CA12CA1CA2CA3 | |
| SCHEMBL11137601 | 0.89 | PLA2G2A (0.62) | PTGS2TP53ALDH1A1HPGDESR1 | |
| SCHEMBL13464234 | 0.86 | PTGS2 (0.65) | PTGS2CA12CA1CA2CA3 | |
| SCHEMBL5150372 | 0.83 | KDM4E (0.62) | PTGS2CA12CA1CA2CA7 | |
| Gallic Acid SCHEMBL9068107 | 0.82 | KDM4E (0.63) | PTGS2CA12CA1CA2CA3 | |
| SCHEMBL6023328 | 0.81 | PLA2G2A (0.66) | CA12CA1CA2CA3CA4 | |
| SCHEMBL13367355 | 0.79 | PTGS2 (0.59) | PTGS2CA12CA1CA2CA3 | |
| SCHEMBL9048230 | 0.78 | CA12 (0.62) | PTGS2CA12CA1CA2CA3 | |
| Propyl Gallate SCHEMBL3696375 | 0.78 | ESR1 (0.71) | CA12CA1CA2CA3CA4 | |
| Gallic Acid SCHEMBL28459555 | 0.78 | LMNA (0.57) | PTGS2CA12CA1CA2CA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996029315-A2 | IMIDAZOLE DERIVATIVES AS HISTAMINE RECEPTOR H3 (ANT)AGONISTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 1996-09-26 | — | — | WO | disclosed |
| EP-0715525-A1 | AQUEOUS FLUID ABSORBENT POLYMERS HAVING A SUPERIOR BALANCE OF ABSORPTIVE PROPERTIES | THE DOW CHEMICAL COMPANY (US) | 1996-06-12 | — | — | EP | disclosed |
| WO-1995005856-A1 | AQUEOUS FLUID ABSORBENT POLYMERS HAVING A SUPERIOR BALANCE OF ABSORPTIVE PROPERTIES | THE DOW CHEMICAL COMPANY (US) | 1995-03-02 | — | — | WO | disclosed |