Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.43 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.40 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.39 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4383862 | 0.94 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2AFFAR1PLA2G4A | |
| SCHEMBL4383472 | 0.90 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2AFFAR1S1PR1 | |
| SCHEMBL4378585 | 0.86 | ALDH1A1 (0.53) | ALDH1A1MEN1KMT2AFFAR1LMNA | |
| SCHEMBL8795425 | 0.80 | FFAR1 (0.39) | FFAR1PLA2G4AS1PR1S1PR3S1PR5 | |
| SCHEMBL4378557 | 0.80 | POLB (0.42) | ALDH1A1FFAR1LMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL4390063 | 0.80 | FFAR1 (0.38) | ALDH1A1MEN1KMT2AFFAR1LMNA | |
| SCHEMBL7961178 | 0.78 | HRH3 (0.58) | ALDH1A1LMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL4379786 | 0.78 | ITGB3 (0.40) | MEN1KMT2AFFAR1PLA2G4AS1PR1 | |
| SCHEMBL2628226 | 0.78 | FFAR1 (0.52) | ALDH1A1MEN1KMT2AFFAR1PLA2G4A | |
| SCHEMBL7977271 | 0.78 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2ALMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996029315-A2 | IMIDAZOLE DERIVATIVES AS HISTAMINE RECEPTOR H3 (ANT)AGONISTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 1996-09-26 | — | — | WO | claimed |