Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4383862 | 0.96 | ALDH1A1 (0.46) | ALDH1A1FFAR1MEN1KMT2ALMNA | |
| SCHEMBL4378585 | 0.94 | ALDH1A1 (0.53) | ALDH1A1FFAR1MEN1KMT2ALMNA | |
| SCHEMBL8934837 | 0.90 | ALDH1A1 (0.45) | ALDH1A1FFAR1MEN1KMT2ALMNA | |
| SCHEMBL4378557 | 0.87 | POLB (0.42) | ALDH1A1FFAR1LMNAL3MBTL1HRH3 | |
| SCHEMBL4384959 | 0.85 | FFAR1 (0.39) | ALDH1A1FFAR1CYP4F2CYP4A11PPARG | |
| SCHEMBL7991257 | 0.83 | CYP3A4 (0.45) | ALDH1A1MEN1KMT2ALMNAL3MBTL1 | |
| SCHEMBL4390063 | 0.82 | FFAR1 (0.38) | ALDH1A1FFAR1MEN1KMT2ALMNA | |
| SCHEMBL4376187 | 0.82 | L3MBTL1 (0.59) | ALDH1A1LMNAL3MBTL1HRH3KDM4E | |
| SCHEMBL4378233 | 0.81 | FFAR1 (0.39) | ALDH1A1FFAR1MEN1KMT2ALMNA | |
| Oxalic Acid SCHEMBL7990912 | 0.81 | MEN1 (0.47) | ALDH1A1FFAR1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760811-B1 | IMIDAZOLE DERIVATIVES AS HISTAMINE RECEPTOR H3 MODULATORS | INST NAT SANTE RECH MED (FR) | 2009-11-18 | — | — | EP | disclosed |
| US-6248765-B1 | ANTIINFLAMMATORY AGENTS; HYPOTENSIVE AGENTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICAL (FR) | 2001-06-19 | — | — | US | disclosed |
| EP-0760811-A1 | IMIDAZOLE DERIVATIVES AS HISTAMINE RECEPTOR H 3? (ANT)AGONISTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 1997-03-12 | — | — | EP | disclosed |
| WO-1996029315-A2 | IMIDAZOLE DERIVATIVES AS HISTAMINE RECEPTOR H3 (ANT)AGONISTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 1996-09-26 | — | — | WO | disclosed |