Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8934805 | 0.87 | SMN1; SMN2 (0.42) | SMN1; SMN2MAPTMAPK1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL8934824 | 0.85 | SMN1; SMN2 (0.41) | SMN1; SMN2MAPTMAPK1NPC1RAB9A | |
| SCHEMBL8788853 | 0.77 | THRB (0.44) | SMN1; SMN2MAPTMAPK1NPC1RAB9A | |
| SCHEMBL3257235 | 0.72 | MEN1 (0.42) | SMN1; SMN2MAPTMAPK1NPC1RAB9A | |
| SCHEMBL3149598 | 0.72 | MEN1 (0.42) | SMN1; SMN2MAPTMAPK1NPC1RAB9A | |
| SCHEMBL14762615 | 0.72 | NPC1 (0.45) | SMN1; SMN2MAPK1NPC1RAB9ALMNA | |
| SCHEMBL14091590 | 0.71 | SMN1; SMN2 (0.58) | SMN1; SMN2MAPTMAPK1NPC1RAB9A | |
| SCHEMBL1390735 | 0.71 | ACACB (0.53) | ALDH1A1KDM4EHSD17B10CYP1A2CYP2C9 | |
| SCHEMBL4470392 | 0.69 | NPC1 (0.52) | SMN1; SMN2MAPK1NPC1RAB9ALMNA | |
| SCHEMBL8289396 | 0.69 | HDAC1 (0.66) | CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996029386-A1 | DETERGENT BUILDER COMPOSITION FOR REDUCING CALCIUM SCALING | RHONE-POULENC CHIMIE (FR) | 1996-09-26 | — | — | WO | disclosed |
| WO-1996029331-A1 | IMIDAZOQUINAZOLINES, DRUGS CONTAINING THESE COMPOUNDS, THEIR USE AND PROCESS FOR THEIR PREPARATION | DR. KARL THOMAE GMBH (DE) | 1996-09-26 | — | — | WO | disclosed |