Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.39 |
| ▸ | RHEB | Q15382 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 2/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.37 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.36 |
| ▸ | NQO2 | P16083 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.36 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3140572 | 0.88 | ALDH1A1 (0.46) | MEN1KMT2AALDH1A1MAPTCYP1A2 | |
| SCHEMBL3257235 | 0.85 | MEN1 (0.42) | MEN1KMT2AALDH1A1MAPTCYP1A2 | |
| SCHEMBL9305044 | 0.83 | PDE3B (0.46) | KMT2AALDH1A1PDE3BPDE3ANPC1 | |
| SCHEMBL1193199 | 0.81 | ALDH1A1 (0.48) | MEN1KMT2AALDH1A1MAPTCYP1A2 | |
| SCHEMBL8788853 | 0.80 | THRB (0.44) | MEN1KMT2AALDH1A1MAPTCYP2C19 | |
| SCHEMBL1193316 | 0.78 | RHEB (0.54) | MEN1KMT2AALDH1A1MAPTRHEB | |
| Hydrochloric Acid SCHEMBL8934824 | 0.77 | SMN1; SMN2 (0.41) | MEN1KMT2AALDH1A1MAPTCYP1A2 | |
| SCHEMBL8934805 | 0.76 | SMN1; SMN2 (0.42) | MEN1KMT2AALDH1A1MAPTCYP1A2 | |
| SCHEMBL9707250 | 0.75 | PDGFRB (0.35) | MEN1KMT2AALDH1A1MAPTCYP1A2 | |
| SCHEMBL4606421 | 0.75 | MMP12 (0.47) | KMT2AALDH1A1NPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1863790-B1 | AMIDE-SUBSTITUTED 8-N-BENZIMIDAZOLES, METHOD FOR THE PRODUCTION THEREOF, AND USE OF THE SAME AS MEDICAMENTS | SANOFI AVENTIS (FR) | 2010-02-10 | — | — | EP | disclosed |