Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.38 |
| ▸ | PTPRC | P08575 | 5/20 | 0.36 |
| ▸ | PTPN13 | Q12923 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28264624 | 0.90 | IDO1 (0.45) | IDO1LTA4HPOLBCYP2D6KMT2A | |
| SCHEMBL28262486 | 0.75 | ALPI (0.51) | LTA4HPOLBSLC1A1 | |
| SCHEMBL28271550 | 0.73 | ALDH1A1 (0.49) | LTA4HSLC1A1KMT2A | |
| SCHEMBL434649 | 0.73 | POLB (0.52) | POLBCYP2D6KMT2ASLC6A4SLC6A3 | |
| SCHEMBL12869912 | 0.72 | LTA4H (0.54) | IDO1LTA4HSLC1A1 | |
| SCHEMBL17375358 | 0.72 | LTA4H (0.54) | IDO1LTA4HSLC1A1 | |
| SCHEMBL685354 | 0.72 | POLB (0.50) | POLBCYP2D6KMT2ASLC6A4SLC6A3 | |
| SCHEMBL27555134 | 0.71 | POLB (0.48) | POLBCYP2D6KMT2A | |
| SCHEMBL4265489 | 0.71 | CYP2D6 (0.41) | POLBCYP2D6KMT2A | |
| SCHEMBL131049 | 0.71 | SLC1A1 (0.55) | LTA4HSLC1A1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996029088-A1 | NOVEL PIPERAZINE DERIVATIVES AS TYPE IL-1 RECEPTOR ANTAGONISTS | AFFYMAX TECHNOLOGIES N.V. (AN) | 1996-09-26 | — | — | WO | disclosed |