Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 6/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.39 |
| ▸ | PPARG | P37231 | 6/20 | 0.39 |
| ▸ | PPARD | Q03181 | 6/20 | 0.39 |
| ▸ | PPARA | Q07869 | 6/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.39 |
| ▸ | TLR2 | O60603 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | FABP4 | P15090 | 2/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.39 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL18395918 | 1.00 | ALDH1A1 (0.48) | ALDH1A1ATMHCAR2TSHRHPGD | |
| Bicarbonate SCHEMBL1261114 | 0.97 | ALDH1A1 (0.50) | ALDH1A1ATMHCAR2TSHRHPGD | |
| Bicarbonate SCHEMBL316752 | 0.97 | ALDH1A1 (0.50) | ALDH1A1ATMHCAR2TSHRHPGD | |
| Bicarbonate SCHEMBL29201354 | 0.95 | ALDH1A1 (0.48) | ALDH1A1ATMHCAR2TSHRHPGD | |
| Bicarbonate SCHEMBL10886257 | 0.90 | NAAA (0.48) | ALDH1A1HCAR2TSHRAKR1B1GPR84 | |
| Acetic Acid SCHEMBL28556071 | 0.90 | ALDH1A1 (0.54) | ALDH1A1ATMHCAR2TSHRHPGD | |
| Acetic Acid SCHEMBL8164986 | 0.90 | ALDH1A1 (0.54) | ALDH1A1ATMHCAR2TSHRHPGD | |
| Bicarbonate SCHEMBL28108460 | 0.90 | NAAA (0.48) | ALDH1A1HCAR2TSHRAKR1B1GPR84 | |
| Bicarbonate SCHEMBL2059473 | 0.90 | NAAA (0.48) | ALDH1A1HCAR2TSHRAKR1B1GPR84 | |
| Bicarbonate SCHEMBL786259 | 0.87 | NAAA (0.52) | ALDH1A1HCAR2TSHRGPR84PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8173048-B2 | Composition for circuit connection film and circuit connection film using the same | CHEIL INDUSTRIES, INC. (KR) | 2012-05-08 | — | — | US | claimed |
| US-20100148130-A1 | Composition for circuit connection film and circuit connection film using the same | KUKDO ADVANCED MATERIALS CO., LTD. (KR) | 2010-06-17 | — | — | US | claimed |
| US-9589696-B2 | Semiconductor device using composition for anisotropic conductive adhesive film or anisotropic conductive adhesive film | CHEIL INDUSTRIES, INC. (KR) | 2017-03-07 | — | — | US | disclosed |
| US-9389338-B2 | Optical member comprising anisotropic conductive film | CHEIL INDUSTRIES, INC. (KR) | 2016-07-12 | — | — | US | disclosed |
| US-9299654-B2 | Anisotropic conductive film composition, anisotropic conductive film, and semiconductor device | CHEIL INDUSTRIES, INC. (KR) | 2016-03-29 | — | — | US | disclosed |
| US-8872357-B2 | Anisotropic conductive film composition and semiconductor device bonded by the same | CHEIL INDUSTRIES, INC. (KR) | 2014-10-28 | — | — | US | disclosed |
| US-8728352-B2 | Electrical connection material and a solar cell including the same | CHEIL INDUSTRIES, INC. (KR) | 2014-05-20 | — | — | US | disclosed |
| US-20130154094-A1 | ANISOTROPIC CONDUCTIVE FILM COMPOSITION, ANISOTROPIC CONDUCTIVE FILM, AND SEMICONDUCTOR DEVICE | CHEIL INDUSTRIES, INC. (KR) | 2013-06-20 | — | — | US | disclosed |
| US-20130119563-A1 | ANISOTROPIC CONDUCTIVE FILM COMPOSITION AND SEMICONDUCTOR DEVICE BONDED BY THE SAME | KUKDO CHEMICAL CO., LTD. (KR) | 2013-05-16 | — | — | US | disclosed |
| US-20130113119-A1 | SEMICONDUCTOR DEVICE USING COMPOSITION FOR ANISOTROPIC CONDUCTIVE ADHESIVE FILM OR ANISOTROPIC CONDUCTIVE ADHESIVE FILM | KUKDO ADVANCED MATERIALS CO., LTD. (KR) | 2013-05-09 | — | — | US | disclosed |
| US-20120141802-A1 | OPTICAL MEMBER COMPRISING ANISOTROPIC CONDUCTIVE FILM | KUKDO CHEMICAL CO., LTD. (KR) | 2012-06-07 | — | — | US | disclosed |
| US-8173048-B2 | Composition for circuit connection film and circuit connection film using the same | CHEIL INDUSTRIES, INC. (KR) | 2012-05-08 | — | — | US | disclosed |
| US-20120080068-A1 | ELECTRICAL CONNECTION MATERIAL AND A SOLAR CELL INCLUDING THE SAME | KUKDO CHEMICAL CO., LTD. (KR) | 2012-04-05 | — | — | US | disclosed |
| US-20100148130-A1 | Composition for circuit connection film and circuit connection film using the same | KUKDO ADVANCED MATERIALS CO., LTD. (KR) | 2010-06-17 | — | — | US | disclosed |
| WO-2007021070-A1 | FILM FOR ANISOTROPIC CONDUCTIVITY AND ELECTRONIC CIRCUITS AND DEVICES USING THE FILM | CHEIL INDUSTRIES INC. (KR) | 2007-02-22 | — | — | WO | disclosed |