Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.52 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.48 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.48 |
| ▸ | PPARG | P37231 | 7/20 | 0.48 |
| ▸ | PPARD | Q03181 | 7/20 | 0.48 |
| ▸ | PPARA | Q07869 | 7/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.48 |
| ▸ | TSHR | P16473 | 5/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TLR2 | O60603 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | FABP4 | P15090 | 2/20 | 0.48 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.48 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL2466923 | 1.00 | NAAA (0.52) | NAAACES2HCAR2EPHX1GPR84 | |
| Bicarbonate SCHEMBL4631149 | 1.00 | NAAA (0.52) | NAAACES2HCAR2EPHX1GPR84 | |
| Bicarbonate SCHEMBL7893413 | 1.00 | NAAA (0.52) | NAAACES2HCAR2EPHX1GPR84 | |
| Bicarbonate SCHEMBL11529637 | 1.00 | NAAA (0.52) | NAAACES2HCAR2EPHX1GPR84 | |
| Bicarbonate SCHEMBL9344673 | 1.00 | NAAA (0.52) | NAAACES2HCAR2EPHX1GPR84 | |
| Bicarbonate SCHEMBL11587440 | 1.00 | NAAA (0.52) | NAAACES2HCAR2EPHX1GPR84 | |
| Bicarbonate SCHEMBL10355758 | 1.00 | NAAA (0.52) | NAAACES2HCAR2EPHX1GPR84 | |
| Bicarbonate SCHEMBL786724 | 1.00 | NAAA (0.52) | NAAACES2HCAR2EPHX1GPR84 | |
| Bicarbonate SCHEMBL8663181 | 1.00 | NAAA (0.52) | NAAACES2HCAR2EPHX1GPR84 | |
| Bicarbonate SCHEMBL14152424 | 1.00 | NAAA (0.52) | NAAACES2HCAR2EPHX1GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 297 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4735933-A2 | SURFACE ACTIVATED CHEMICAL VAPOR DEPOSITION AND USES THEREOF | Gvd Corporation (US) | 2026-05-06 | — | — | EP | claimed |
| EP-4735935-A2 | SURFACE ACTIVATED CHEMICAL VAPOR DEPOSITION AND USES THEREOF | Gvd Corporation (US) | 2026-05-06 | — | — | EP | claimed |
| US-20250353967-A1 | CURABLE SILOXANE RESIN COMPOSITION AND FILM INCLUDING THE SAME | KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2025-11-20 | — | — | US | claimed |
| US-12331164-B2 | Curable siloxane resin composition | KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2025-06-17 | — | — | US | claimed |
| WO-2025007115-A2 | SURFACE ACTIVATED CHEMICAL VAPOR DEPOSITION AND USES THEREOF | GVD CORPORATION (US) | 2025-01-02 | — | — | WO | claimed |
| WO-2025007129-A2 | SURFACE ACTIVATED CHEMICAL VAPOR DEPOSITION AND USES THEREOF | GVD CORPORATION (US) | 2025-01-02 | — | — | WO | claimed |
| EP-4321425-A1 | ROLL WITH SELF-FUSING AND ANTIFOULING PROTECTION TAPE AND USE OF THE TAPE FOR WRAPPING OBJECTS | OCEAN-Tape GmbH (DE) | 2024-02-14 | — | — | EP | claimed |
| US-20230078587-A1 | CURABLE SILOXANE RESIN COMPOSITION | KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2023-03-16 | — | — | US | claimed |
| US-10961153-B2 | Composition for synthetic stone | Mitsubishi Chemical UK Limited (GB) | 2021-03-30 | — | — | US | claimed |
| US-20190100461-A1 | A COMPOSITION FOR SYNTHETIC STONE | Mitsubishi Chemical UK Limited (GB) | 2019-04-04 | — | — | US | claimed |
| EP-0814101-A2 | Improved polycarboxylic acids | 3V SIGMA S.p.A (IT) | 1997-12-29 | — | — | EP | claimed |
| US-5663253-A | THICKENERS | 3V INC. (US) | 1997-09-02 | — | — | US | claimed |
| EP-0517290-B1 | Initiator suspensions, their preparation and use | AKZO NOBEL NV (NL) | 1995-06-07 | — | — | EP | claimed |
| EP-0328725-B1 | Polycarboxylic acids with higher thickening capacity and better clarity | GOODRICH CO B F (US) | 1995-05-03 | — | — | EP | claimed |
| US-5342911-A | Solvent mixture containing methylene chloride and an ester | 3V INC. (US) | 1994-08-30 | — | — | US | claimed |
| US-5017666-A | Solution polymerization | PPG INDUSTRIES, INC. (US) | 1991-05-21 | — | — | US | claimed |
| US-4563510-A | Process for the preparation of polymer latex | SINTEF (NO) | 1986-01-07 | — | — | US | claimed |
| EP-0144782-A2 | Polyol(allyl carbonate) compositions and polymerizates prepared therefrom | PPG INDUSTRIES, INC. (US) | 1985-06-19 | — | — | EP | claimed |
| US-4232141-A | ADDING AN AQUEOUS DISPERSION OF POWDERED INITIATOR; EMULSION POLYMERIZATION | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1980-11-04 | — | — | US | claimed |
| US-4024326-A | Process for preparing ethylene-carbon monoxide copolymers using a peroxydicarbonate catalyst | ATLANTIC RICHFIELD COMPANY (US) | 1977-05-17 | — | — | US | claimed |