SCHEMBL8935122

SCHEMBL8935122

C=CC(N)(C(=O)O)C(=O)O

nearest known ligand 0.37

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.37
ALDH1A1 P00352 2/20 0.35
TSHR P16473 2/20 0.35
FGFR4 P22455 1/20 0.35
CYP2C19 P33261 1/20 0.31
TP53 P04637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7478604 0.75
SCHEMBL13083468 0.75
SCHEMBL27405198 0.75 DGAT1 (0.38) CYP2C19
SCHEMBL9573116 0.73 ALDH1A1 (0.40) LMNAALDH1A1TSHRFGFR4
Hydrochloric Acid SCHEMBL21609283 0.73 LMNA (0.35) LMNAALDH1A1TSHRFGFR4CYP2C19
SCHEMBL30636058 0.71 ALDH1A1 (0.32) ALDH1A1TSHRTP53
SCHEMBL5165968 0.71
SCHEMBL7152313 0.71
SCHEMBL6765110 0.71
SCHEMBL5165964 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108409972-A Phosphorus nitrogen sulphur macromolecular carbon forming agent and its preparation method and application 苏州安鸿泰新材料有限公司 2018-08-17 CN claimed
CN-108409972-A Phosphorus nitrogen sulphur macromolecular carbon forming agent and its preparation method and application 苏州安鸿泰新材料有限公司 2018-08-17 CN disclosed
CN-1067516-C Insoluble polymer bactericidal agent and preparation thereof CHINA PETROCHEMICAL GEN CORP (CN) 2001-06-27 CN disclosed
CN-1209949-A Insoluble polymer bactericidal agent and preparation thereof CHINA PETROCHEMICAL GEN CORP (CN) 1999-03-10 CN disclosed
EP-0574530-A4 ENDOTHELIN ANTAGONISTS RES CORP TECHNOLOGIES INC (US) 1996-04-03 EP disclosed
US-5492892-A USING A CYCLIC POLYPEPTIDE; VASODILATION ANDERSEN THOMAS T (US) 1996-02-20 US disclosed
EP-0574530-A1 ENDOTHELIN ANTAGONISTS RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 1993-12-22 EP disclosed
WO-1992015321-A1 ENDOTHELIN ANTAGONISTS RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 1992-09-17 WO disclosed
EP-0112580-B1 PROCESS FOR PREPARING PHOSPHONOMETHYLATED AMINO ACIDS STAUFFER CHEMICAL COMPANY (US) 1986-05-21 EP disclosed