Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | STAT3 | P40763 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Triaziquone SCHEMBL7715400 | 0.96 | TP53 (0.35) | TP53MAPTSTAT3HTTSMN1; SMN2 | |
| Triaziquone SCHEMBL9011631 | 0.82 | TP53 (0.37) | TP53MAPTSTAT3HTTSMN1; SMN2 | |
| Triaziquone SCHEMBL5081824 | 0.80 | TP53 (0.36) | TP53MAPTSTAT3HTTSMN1; SMN2 | |
| Triaziquone SCHEMBL17065242 | 0.80 | DNMT1 (0.34) | TP53MAPTSTAT3HTTSMN1; SMN2 | |
| Triaziquone SCHEMBL4081043 | 0.80 | DNMT1 (0.36) | TP53MAPTSTAT3HTTSMN1; SMN2 | |
| Triaziquone SCHEMBL11428634 | 0.77 | DNMT1 (0.41) | TP53MAPTSTAT3HTTSMN1; SMN2 | |
| Triaziquone SCHEMBL242425 | 0.77 | DNMT1 (0.41) | TP53MAPTSTAT3HTTSMN1; SMN2 | |
| Triaziquone SCHEMBL8303 | 0.76 | DNMT1 (0.48) | TP53MAPTSTAT3HTTSMN1; SMN2 | |
| Triaziquone SCHEMBL21358774 | 0.75 | MAPT (0.43) | TP53MAPTSTAT3HTTSMN1; SMN2 | |
| Triaziquone SCHEMBL610295 | 0.75 | DNMT1 (0.42) | TP53MAPTSTAT3HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0625054-A4 | STABILIZED RADIOPHARMACEUTICAL KITS. | MALLINCKRODT MEDICAL INC (US) | 1996-04-17 | — | — | EP | disclosed |
| EP-0625054-A1 | STABILIZED RADIOPHARMACEUTICAL KITS | MALLINCKRODT MEDICAL, INC. (US) | 1994-11-23 | — | — | EP | disclosed |
| WO-1993015765-A1 | STABILIZED RADIOPHARMACEUTICAL KITS | MALLINCKRODT MEDICAL, INC. (US) | 1993-08-19 | — | — | WO | disclosed |