Sugi Predict

Sugi Predict / Compounds / Triaziquone

Triaziquone

Triaziquone

SCHEMBL242425

O=C1C=C(N2CC2)C(=O)C(N2CC2)=C1N1CC1.OCP

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ DNMT1 P26358 1/20 0.41
▸ TP53 P04637 1/20 0.39
▸ MAPT P10636 1/20 0.39
▸ STAT3 P40763 1/20 0.39
▸ HTT P42858 1/20 0.39
▸ SMN1; SMN2 Q16637 1/20 0.39
▸ NSD2 O96028 3/20 0.34
▸ APAF1 O14727 2/20 0.34
▸ TDP2 O95551 2/20 0.34
▸ HKDC1 Q2TB90 2/20 0.34
▸ CYP1A2 P05177 1/20 0.33
▸ CYP3A4 P08684 1/20 0.33
▸ CYP2D6 P10635 1/20 0.33
▸ TSHR P16473 1/20 0.33
▸ MAPK1 P28482 1/20 0.33
▸ HIF1A Q16665 1/20 0.33
▸ MEN1 O00255 1/20 0.33
▸ NPC1 O15118 1/20 0.33
▸ RAB9A P51151 1/20 0.33
▸ GALK1 P51570 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Triaziquone SCHEMBL11428634 0.89 DNMT1 (0.41) DNMT1TP53MAPTSTAT3HTT
Triaziquone SCHEMBL11350903 0.89 HTT (0.42) DNMT1TP53MAPTSTAT3HTT
Triaziquone SCHEMBL5800741 0.89 DNMT1 (0.41) DNMT1TP53MAPTSTAT3HTT
Triaziquone SCHEMBL4081043 0.89 DNMT1 (0.36) DNMT1TP53MAPTSTAT3HTT
Triaziquone SCHEMBL8303 0.88 DNMT1 (0.48) DNMT1TP53MAPTSTAT3HTT
Triaziquone SCHEMBL6387848 0.87 MAPT (0.41) DNMT1TP53MAPTSTAT3HTT
Triaziquone SCHEMBL7783197 0.86 MAPT (0.46) DNMT1TP53MAPTSTAT3HTT
Triaziquone SCHEMBL8993238 0.86 DNMT1 (0.47) DNMT1TP53MAPTSTAT3HTT
Triaziquone SCHEMBL1538515 0.86 DNMT1 (0.47) DNMT1TP53MAPTSTAT3HTT
Triaziquone SCHEMBL7738777 0.86 DNMT1 (0.47) DNMT1TP53MAPTSTAT3HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3204458-B1 INK ADDITIVE COMBINATIONS FOR IMPROVING PRINTHEAD LIFETIME MEMJET TECHNOLOGY LTD (IE) 2018-09-26 — — EP claimed
US-6361767-B1 REDUCING DISULFIDE BONDS OF HAIR KERATIN FIBERS WITH AQUEOUS REDUCING AGENT SOLUTION CONSISTING OF PHOSPHINES OR SALT AND MINERAL OR ORGANIC ACID, OR THIOLS AND POLYQUATERNARY AMMONIUM HYDROXIDE, FIXING ACTIVE COLORANT ON SITES PRODUCED L'OREAL (FR) 2002-03-26 — — US claimed
US-12247107-B2 Flame retardant polymers and methods of making ALEXIUM, INC. (US) 2025-03-11 — — US disclosed
US-20210147636-A1 FLAME RETARDANT POLYMERS AND METHODS OF MAKING ALEXIUM, INC. 2021-05-20 — — US disclosed
EP-3775022-A1 FLAME RETARDANT POLYMERS AND METHODS OF MAKING Alexium, Inc. (US) 2021-02-17 — — EP disclosed
WO-2019200333-A1 FLAME RETARDANT POLYMERS AND METHODS OF MAKING ALEXIUM, INC. (US) 2019-10-17 — — WO disclosed
CN-105555791-B Method for preparing tris hydroxymethyl phosphine 麦格派聚合物公司 2018-01-12 — — CN disclosed
US-20120003260-A1 Solid-Phase and Solution-Phase Synthesis of Glycosylphosphatidylinositol Glycans MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2012-01-05 — — US disclosed
US-7943594-B2 Solid-phase and solution-phase synthesis of glycosylphosphatidylinositol glycans MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2011-05-17 — — US disclosed
US-20100261185-A1 LABELED ENZYME COMPOSITIONS, METHODS AND SYSTEMS Life Technologies Corporation (US) 2010-10-14 — — US disclosed
US-20100204068-A1 Methods for controlling depolymerization of polymer compositions RHODIA OPERATIONS (FR) 2010-08-12 — — US disclosed
EP-1315559-A2 APPARATUS AND METHODS FOR THE AUTOMATED SYNTHESIS OF OLIGOSACCHARIDES Massachusetts Institute Of Technology (US) 2003-06-04 — — EP disclosed
WO-2003017930-A2 REAGENTS THAT FACILITATE THE PURIFICATION OF COMPOUNDS SYNTHESIZED ON A SOLID SUPPORT MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2003-03-06 — — WO disclosed
WO-2002080867-A2 HAIR COLOURING COMPOSITIONS UNILEVER PLC (GB) 2002-10-17 — — WO disclosed
WO-2002080868-A1 METHOD OF COLOURING HAIR UNILEVER PLC (GB) 2002-10-17 — — WO disclosed
US-20020085964-A1 Apparatus and methods for the automated synthesis of oligosaccharides MASSACHUSETTS INSTITUTE OF TECHNOLOGY 2002-07-04 — — US disclosed
WO-2002016384-A2 APPARATUS AND METHODS FOR THE AUTOMATED SYNTHESIS OF OLIGOSACCHARIDES MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2002-02-28 — — WO disclosed
WO-1996030056-A1 HYDROXYALKYL PHOSPHINE COMPOUNDS FOR USE AS DIAGNOSTIC AND THERAPEUTIC PHARMACEUTICALS AND METHOD OF MAKING SAME THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) 1996-10-03 — — WO disclosed
US-4071501-A Water soluble adduct of hydroxymethyl phosphorous compound and ammonia or amine compound and method of preparation THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 1978-01-31 — — US disclosed
US-3953166-A HYDROXYMETHYL-PHOSPHONIUM COMPOUND, PHENOLIC RESINS THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 1976-04-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120003260-A1 Solid-Phase and Solution-Phase Synthesis of Glycosylphosphatidylinositol Glycans GPI, ALG1, FUT5 DNMT1 4686/4885TP53 3492/4885MAPT 4461/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.