Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNMT1 | P26358 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Triaziquone SCHEMBL4081043 | 0.94 | DNMT1 (0.36) | DNMT1TP53MAPTSTAT3HTT | |
| Triaziquone SCHEMBL242425 | 0.86 | DNMT1 (0.41) | DNMT1TP53MAPTSTAT3HTT | |
| Triaziquone SCHEMBL7938206 | 0.85 | LMNA (0.38) | DNMT1TP53MAPTSTAT3HTT | |
| Triaziquone SCHEMBL9798150 | 0.82 | TP53 (0.37) | DNMT1TP53MAPTSTAT3HTT | |
| Triaziquone SCHEMBL9011631 | 0.82 | TP53 (0.37) | DNMT1TP53MAPTSTAT3HTT | |
| Triaziquone SCHEMBL8935221 | 0.80 | TP53 (0.34) | DNMT1TP53MAPTSTAT3HTT | |
| Triaziquone SCHEMBL1961248 | 0.80 | DNMT1 (0.39) | DNMT1TP53MAPTSTAT3HTT | |
| Triaziquone SCHEMBL11350903 | 0.79 | HTT (0.42) | DNMT1TP53MAPTSTAT3HTT | |
| Triaziquone SCHEMBL11428634 | 0.79 | DNMT1 (0.41) | DNMT1TP53MAPTSTAT3HTT | |
| Triaziquone SCHEMBL8303 | 0.79 | DNMT1 (0.48) | DNMT1TP53MAPTSTAT3HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10011751-B2 | Phosphine-catalyzed, michael addition-curable sulfur-containing polymer compositions | PRC-DESOTO INTERNATIONAL, INC. (US) | 2018-07-03 | — | — | US | disclosed |
| EP-3114155-B1 | PHOSPHINE-CATALYZED, MICHAEL ADDITION-CURABLE SULFUR-CONTAINING POLYMER COMPOSITIONS | PRC DESOTO INT INC (US) | 2018-06-06 | — | — | EP | disclosed |
| EP-3114155-A1 | PHOSPHINE-CATALYZED, MICHAEL ADDITION-CURABLE SULFUR-CONTAINING POLYMER COMPOSITIONS | PRC-Desoto International, Inc. (US) | 2017-01-11 | — | — | EP | disclosed |
| US-20160186025-A1 | PHOSPHINE-CATALYZED, MICHAEL ADDITION-CURABLE SULFUR-CONTAINING POLYMER COMPOSITIONS | PRC DESOTO INT INC (US) | 2016-06-30 | — | — | US | disclosed |
| WO-2015134843-A1 | PHOSPHINE-CATALYZED, MICHAEL ADDITION-CURABLE SULFUR-CONTAINING POLYMER COMPOSITIONS | PRC-DESOTO INTERNATIONAL, INC. (US) | 2015-09-11 | — | — | WO | disclosed |