Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G10 | O15496 | 4/20 | 0.47 |
| ▸ | PLA2G2A | P14555 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | ACACA | Q13085 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | MME | P08473 | 3/20 | 0.39 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.39 |
| ▸ | F7 | P08709 | 1/20 | 0.39 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.38 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.38 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.38 |
| ▸ | PLA2G12B | Q9BX93 | 1/20 | 0.38 |
| ▸ | PLA2G12A | Q9BZM1 | 1/20 | 0.38 |
| ▸ | PLA2G2F | Q9BZM2 | 1/20 | 0.38 |
| ▸ | PLA2G3 | Q9NZ20 | 1/20 | 0.38 |
| ▸ | PLA2G2E | Q9NZK7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23699060 | 0.75 | MME (0.51) | MME | |
| SCHEMBL4984168 | 0.75 | MME (0.51) | MME | |
| SCHEMBL4990065 | 0.73 | ALDH1A1 (0.47) | LMNAMME | |
| SCHEMBL20072245 | 0.73 | TAAR1 (0.49) | EPHX1MME | |
| SCHEMBL7402142 | 0.73 | ACACB (0.50) | PLA2G10PLA2G2ALMNAEPHX1ACACB | |
| SCHEMBL28402070 | 0.72 | MME (0.46) | MME | |
| SCHEMBL5607432 | 0.72 | CYP2C19 (0.46) | LMNAEPHX1MME | |
| SCHEMBL31240124 | 0.72 | PTGS2 (0.65) | LMNAKEAP1NFE2L2 | |
| SCHEMBL9114516 | 0.72 | PLA2G10 (0.46) | PLA2G10PLA2G2ALMNAEPHX1ACACB | |
| SCHEMBL7403760 | 0.71 | CYP1A2 (0.53) | PLA2G10PLA2G2ALMNAEPHX1LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5502079-A | TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS | FARMITALIA CARLO ERBA S.R.L. (IT) | 1996-03-26 | — | — | US | disclosed |
| EP-0400495-A1 | N-phenylalkyl substituted alfa-amino carboxamide derivatives and process for their preparation | FARMITALIA CARLO ERBA S.r.l. (IT) | 1990-12-05 | — | — | EP | disclosed |