Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TRPM8 | Q7Z2W7 | 6/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | F9 | P00740 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27309675 | 0.81 | PARP10 (0.57) | CYP1A2CYP2C19GAARAB9AL3MBTL1 | |
| Hydrochloric Acid SCHEMBL27353104 | 0.80 | PARP10 (0.56) | GAARAB9AL3MBTL1SMN1; SMN2LTA4H | |
| SCHEMBL27311683 | 0.80 | PPARG (0.53) | L3MBTL1BLMSMN1; SMN2 | |
| SCHEMBL8935338 | 0.79 | PARP10 (0.48) | BLM | |
| SCHEMBL28904310 | 0.79 | NPC1 (0.56) | POLBRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL8935371 | 0.79 | GAA (0.56) | POLBGAARAB9ANPC1L3MBTL1 | |
| SCHEMBL8935384 | 0.78 | PARP10 (0.43) | TRPM8HPGDBLMLTA4H | |
| SCHEMBL28500733 | 0.77 | MAOB (0.61) | — | |
| SCHEMBL28510234 | 0.77 | MAOB (0.57) | RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL28503302 | 0.77 | PARP10 (0.45) | POLBRAB9ABLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5502079-A | TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS | FARMITALIA CARLO ERBA S.R.L. (IT) | 1996-03-26 | — | — | US | disclosed |