Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 4/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 4/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | RXRB | P28702 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8935338 | 0.96 | PARP10 (0.48) | PARP10BLMMAOBNR4A2RXRA | |
| SCHEMBL27344680 | 0.90 | MMP13 (0.44) | PARP10MAOBMAPK14MMP2MMP13 | |
| SCHEMBL28491503 | 0.87 | PKM (0.45) | PARP10MAOBALDH1A1RAB9AKDM1A | |
| SCHEMBL27311683 | 0.86 | PPARG (0.53) | PARP10BLMMAOBNR4A2ALDH1A1 | |
| SCHEMBL28904310 | 0.84 | NPC1 (0.56) | PARP10MAOBALDH1A1POLBMAPT | |
| SCHEMBL27309675 | 0.84 | PARP10 (0.57) | PARP10MAOBNR4A2MAPTRAB9A | |
| SCHEMBL28505503 | 0.84 | RAB9A (0.51) | BLMALDH1A1MAPTRAB9AMMP2 | |
| SCHEMBL28510234 | 0.83 | MAOB (0.57) | PARP10MAOBNR4A2RAB9A | |
| SCHEMBL28500733 | 0.83 | MAOB (0.61) | PARP10MAOBNR4A2 | |
| Hydrochloric Acid SCHEMBL27353104 | 0.83 | PARP10 (0.56) | PARP10MAOBNR4A2MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107522654-B | Novel alpha-aminoamide derivatives and medicinal use thereof | 中国人民解放军军事医学科学院毒物药物研究所 | 2020-09-01 | — | — | CN | disclosed |