Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | ACACB | O00763 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.40 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.40 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27309675 | 0.80 | PARP10 (0.57) | GAARAB9ASMN1; SMN2L3MBTL1KMT2A | |
| Hydrochloric Acid SCHEMBL27353104 | 0.79 | PARP10 (0.56) | GAARAB9ASMN1; SMN2L3MBTL1KMT2A | |
| SCHEMBL27311683 | 0.79 | PPARG (0.53) | ALDH1A1SMN1; SMN2L3MBTL1BLM | |
| SCHEMBL8935261 | 0.79 | POLB (0.47) | GAANPC1RAB9AMAPK1HPGD | |
| SCHEMBL8935272 | 0.79 | ACACB (0.47) | ACACBNPC1RAB9ABLMSLC1A3 | |
| SCHEMBL28904310 | 0.78 | NPC1 (0.56) | NPC1RAB9AALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL28500733 | 0.76 | MAOB (0.61) | — | |
| SCHEMBL28510234 | 0.76 | MAOB (0.57) | NPC1RAB9ASMN1; SMN2KMT2AHSD17B10 | |
| SCHEMBL8935338 | 0.75 | PARP10 (0.48) | BLM | |
| SCHEMBL8935443 | 0.75 | MAOB (0.60) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5502079-A | TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS | FARMITALIA CARLO ERBA S.R.L. (IT) | 1996-03-26 | — | — | US | disclosed |