Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 4/20 | 0.48 |
| ▸ | MAOB | P27338 | 4/20 | 0.47 |
| ▸ | MMP2 | P08253 | 2/20 | 0.44 |
| ▸ | MMP13 | P45452 | 2/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | RXRB | P28702 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28503302 | 0.96 | PARP10 (0.45) | PARP10MAOBMMP2MMP13MAPK14 | |
| SCHEMBL27344680 | 0.94 | MMP13 (0.44) | PARP10MAOBMMP2MMP13MAPK14 | |
| SCHEMBL28904310 | 0.86 | NPC1 (0.56) | PARP10MAOB | |
| SCHEMBL27309675 | 0.86 | PARP10 (0.57) | PARP10MAOBNR4A2 | |
| SCHEMBL28500733 | 0.85 | MAOB (0.61) | PARP10MAOBNR4A2 | |
| SCHEMBL28510234 | 0.85 | MAOB (0.57) | PARP10MAOBNR4A2 | |
| Hydrochloric Acid SCHEMBL27353104 | 0.85 | PARP10 (0.56) | PARP10MAOBNR4A2 | |
| SCHEMBL8935266 | 0.85 | MMP13 (0.49) | MMP2MMP13MMP1MMP9 | |
| SCHEMBL27311683 | 0.85 | PPARG (0.53) | PARP10MAOBNR4A2BLM | |
| SCHEMBL28491503 | 0.83 | PKM (0.45) | PARP10MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5502079-A | TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS | FARMITALIA CARLO ERBA S.R.L. (IT) | 1996-03-26 | — | — | US | disclosed |