Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.47 |
| ▸ | PARP10 | Q53GL7 | 5/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | CETP | P11597 | 1/20 | 0.37 |
| ▸ | PLK1 | P53350 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28904310 | 0.81 | NPC1 (0.56) | PARP10MAOBNPC1RAB9A | |
| SCHEMBL27309675 | 0.81 | PARP10 (0.57) | PARP10NR4A2MAOBRAB9AALOX5 | |
| SCHEMBL28510234 | 0.80 | MAOB (0.57) | PARP10NR4A2MAOBNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL27353104 | 0.80 | PARP10 (0.56) | PARP10NR4A2MAOBRAB9AALOX5 | |
| SCHEMBL28500733 | 0.80 | MAOB (0.61) | PARP10NR4A2MAOB | |
| SCHEMBL27311683 | 0.80 | PPARG (0.53) | PARP10BLMNR4A2MAOBALOX5 | |
| SCHEMBL8935338 | 0.79 | PARP10 (0.48) | PARP10BLMNR4A2RXRARXRB | |
| SCHEMBL8935371 | 0.79 | GAA (0.56) | ACACBBLMSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL8935384 | 0.78 | PARP10 (0.43) | PARP10BLMSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL28503302 | 0.77 | PARP10 (0.45) | PARP10BLMNR4A2RXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5502079-A | TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS | FARMITALIA CARLO ERBA S.R.L. (IT) | 1996-03-26 | — | — | US | disclosed |