Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 4/20 | 0.57 |
| ▸ | PRMT6 | Q96LA8 | 4/20 | 0.57 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | LTA4H | P09960 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.52 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8935468 | 0.85 | CARM1 (0.58) | CARM1PRMT6ALDH1A1MEN1KMT2A | |
| SCHEMBL6461987 | 0.82 | KMT2A (0.63) | CARM1PRMT6ALDH1A1MEN1KMT2A | |
| SCHEMBL2236118 | 0.82 | KMT2A (0.63) | CARM1PRMT6ALDH1A1MEN1KMT2A | |
| SCHEMBL1790978 | 0.82 | KMT2A (0.63) | CARM1PRMT6ALDH1A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL5966886 | 0.81 | CARM1 (0.62) | CARM1PRMT6ALDH1A1MEN1KMT2A | |
| SCHEMBL1067813 | 0.80 | HRH3 (0.61) | FFAR1 | |
| SCHEMBL9130764 | 0.80 | HRH3 (0.61) | FFAR1 | |
| SCHEMBL8935389 | 0.80 | LMNA (0.67) | FFAR1LMNAALDH1A1S1PR1S1PR3 | |
| SCHEMBL10423181 | 0.77 | KMT2A (0.77) | ALDH1A1KMT2A | |
| SCHEMBL4653157 | 0.77 | BACE1 (0.63) | CARM1PRMT6LMNAALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5502079-A | TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS | FARMITALIA CARLO ERBA S.R.L. (IT) | 1996-03-26 | — | — | US | disclosed |