Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | TSHR | P16473 | 2/20 | 0.66 |
| ▸ | RECQL | P46063 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.62 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.59 |
| ▸ | KDM1A | O60341 | 1/20 | 0.59 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.58 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.57 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.54 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8935458 | 0.84 | GAA (0.66) | LMNAALDH1A1TRPV1GAAHDAC3 | |
| SCHEMBL7353744 | 0.81 | GAA (0.75) | TSHRRECQLALDH1A1TRPV1GAA | |
| SCHEMBL18376355 | 0.80 | TSHR (0.59) | LMNATSHRRECQLALDH1A1FFAR1 | |
| SCHEMBL8635975 | 0.80 | LTA4H (0.64) | LMNARECQLALDH1A1TAAR1 | |
| Hydrochloric Acid SCHEMBL1128739 | 0.80 | GAA (0.72) | TSHRRECQLALDH1A1TRPV1GAA | |
| SCHEMBL8935401 | 0.80 | CARM1 (0.57) | LMNATSHRRECQLALDH1A1FFAR1 | |
| SCHEMBL31329317 | 0.78 | ALDH1A1 (1.00) | LMNATSHRALDH1A1TRPV1GAA | |
| SCHEMBL3435489 | 0.78 | TRPV1 (0.84) | LMNAALDH1A1TRPV1GAAHDAC3 | |
| SCHEMBL13886620 | 0.78 | HTR2A (0.68) | FFAR1TAAR1S1PR1S1PR3 | |
| SCHEMBL453501 | 0.78 | FFAR1 (0.63) | FFAR1TAAR1S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5502079-A | TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS | FARMITALIA CARLO ERBA S.R.L. (IT) | 1996-03-26 | — | — | US | disclosed |