Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | CARM1 | Q86X55 | 3/20 | 0.59 |
| ▸ | PRMT6 | Q96LA8 | 3/20 | 0.59 |
| ▸ | MME | P08473 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.55 |
| ▸ | MMP8 | P22894 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1790978 | 1.00 | KMT2A (0.63) | KMT2ACARM1PRMT6MMEALDH1A1 | |
| SCHEMBL2236118 | 1.00 | KMT2A (0.63) | KMT2ACARM1PRMT6MMEALDH1A1 | |
| Hydrochloric Acid SCHEMBL5966886 | 0.98 | CARM1 (0.62) | KMT2ACARM1PRMT6MMEALDH1A1 | |
| SCHEMBL8935468 | 0.93 | CARM1 (0.58) | KMT2ACARM1PRMT6MMEALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL2396342 | 0.91 | ALDH1A1 (0.56) | KMT2ACARM1PRMT6MMEALDH1A1 | |
| SCHEMBL4653157 | 0.90 | BACE1 (0.63) | KMT2ACARM1PRMT6ALDH1A1MEN1 | |
| SCHEMBL1752390 | 0.90 | BACE1 (0.63) | KMT2ACARM1PRMT6ALDH1A1MEN1 | |
| SCHEMBL24347008 | 0.89 | MMP8 (0.63) | KMT2ACARM1PRMT6MMEALDH1A1 | |
| SCHEMBL15602694 | 0.87 | CARM1 (0.57) | KMT2ACARM1PRMT6 | |
| SCHEMBL1790982 | 0.86 | KMT2A (0.59) | KMT2AMMEALDH1A1MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8059517-A | — | — | None | — | — | JP | disclosed |
| US-20250042848-A1 | DEUTERATED FUNCTIONALIZED DERIVATIVES OF alpha-ALANINE, IN PARTICULAR FOR THE TREATMENT OF NEUROLOGICAL DISEASES | UNIWERSYTET JAGIELLONSKI (PL) | 2025-02-06 | — | — | US | disclosed |
| EP-4436954-A1 | DEUTERATED FUNCTIONALIZED DERIVATIVES OF ?-ALANINE, IN PARTICULAR FOR THE TREATMENT OF NEUROLOGICAL DISEASES | UNIWERSYTET JAGIELLONSKI (PL) | 2024-10-02 | — | — | EP | disclosed |
| CN-118302410-A | Deuterated functionalized derivatives of alpha-alanine, in particular for the treatment of neurological diseases | 雅盖隆大学 | 2024-07-05 | — | — | CN | disclosed |
| WO-2023096512-A1 | DEUTERATED FUNCTIONALIZED DERIVATIVES OF α-ALANINE, IN PARTICULAR FOR THE TREATMENT OF NEUROLOGICAL DISEASES | Uniwersytet Jagielloński (PL) | 2023-06-01 | — | — | WO | disclosed |
| CN-115715219-A | Water soluble, modified amino acid derivatives for the treatment of neurological diseases and selected psychiatric disorders | 雅盖隆大学 | 2023-02-24 | — | — | CN | disclosed |
| CN-113767088-A | Modified amino acid derivatives for the treatment of neurological diseases and selective psychiatric disorders | 雅盖隆大学 | 2021-12-07 | — | — | CN | disclosed |
| US-10968183-B2 | Small molecule FIEL1 inhibitor in inflammatory and fibrotic lung injury | University of Pittsburgh—of the Commonwealth System of Higher Education (US) | 2021-04-06 | — | — | US | disclosed |
| US-10344003-B2 | Small molecule FIEL1 inhibitor in inflammatory and fibrotic lung injury | University of Pittsburgh—of the Commonwealth System of Higher Education (US) | 2019-07-09 | — | — | US | disclosed |
| US-20180141916-A1 | NOVEL SMALL MOLECULE FIEL1 INHIBITOR IN INFLAMMATORY AND FIBROTIC LUNG INJURY | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2018-05-24 | — | — | US | disclosed |
| US-5773475-A | DIPEPTIDES FOR CENTRAL NERVOUS SYSTEM DISORDERS | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1998-06-30 | — | — | US | disclosed |
| US-5654301-A | Lacosamide FDA Orange book listed patent | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1997-08-05 | — | — | US | disclosed |
| JP-H0859517-A | OPTICAL RESOLUTION AGENT AND PRODUCTION OF OPTICALLY ACTIVE TETRAHYDROFURAN-CARBOXYLIC ACID USING THE SAME | TORAY IND INC | 1996-03-05 | — | — | JP | disclosed |
| US-5378729-A | Diamide derivatives | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1995-01-03 | — | — | US | disclosed |
| WO-1992021648-A1 | AMINO ACID DERIVATIVE ANTICONVULSANT | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1992-12-10 | — | — | WO | disclosed |
| EP-0194464-B1 | AMINO ACID DERIVATIVES AND USE THEREOF FOR THE PREPARATION OF AN ANTICONVULSANT | Research Corporation Technologies, Inc. (a Delaware corp.) (US) | 1991-04-03 | — | — | EP | disclosed |
| US-4766109-A | HYPOTENSIVE AGENTS | SCHERING CORPORATION (US) | 1988-08-23 | — | — | US | disclosed |
| EP-0263506-A2 | Anticonvulsant composition containing amino acid derivative and use of said amino acid derivative | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1988-04-13 | — | — | EP | disclosed |
| EP-0194464-A1 | Amino acid derivatives and use thereof for the preparation of an anticonvulsant | Research Corporation Technologies, Inc. (a Delaware corp.) (US) | 1986-09-17 | — | — | EP | disclosed |
| JP-H00859517-A | — | — | 0001-01-01 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10344003-B2 | Small molecule FIEL1 inhibitor in inflammatory and fibrotic lung injury | FIP1L1, TRIM28, TFPI2 | KMT2A 3338/4885CARM1 2404/4885PRMT6 3179/4885 |
| US-20180141916-A1 | NOVEL SMALL MOLECULE FIEL1 INHIBITOR IN INFLAMMATORY AND FIBROTIC LUNG INJURY | FIP1L1, TRIM28, TFPI2 | KMT2A 3347/4885CARM1 2517/4885PRMT6 3197/4885 |
| US-20250042848-A1 | DEUTERATED FUNCTIONALIZED DERIVATIVES OF alpha-ALANINE, IN PARTICULAR FOR THE TREATMENT OF NEUROLOGICAL DISEASES | AADAT, AAAS, ABAT | KMT2A 2624/4885CARM1 2988/4885PRMT6 882/4885 |
| US-10968183-B2 | Small molecule FIEL1 inhibitor in inflammatory and fibrotic lung injury | FIP1L1, TRIM28, TFPI2 | KMT2A 3338/4885CARM1 2404/4885PRMT6 3179/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.