Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | PPARA | Q07869 | 2/20 | 0.41 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 2/20 | 0.40 |
| ▸ | FCER2 | P06734 | 2/20 | 0.40 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8935431 | 1.00 | MEN1 (0.44) | MEN1KMT2AKDM4ESLC6A4POLB | |
| SCHEMBL10013375 | 0.87 | PSMB5 (0.46) | KMT2AMMP1FCER2ADAM17PDCD1 | |
| SCHEMBL8935308 | 0.85 | PDCD1 (0.44) | LMNASMN1; SMN2MMP1FCER2PDCD1 | |
| SCHEMBL8935301 | 0.85 | PDCD1 (0.44) | LMNASMN1; SMN2MMP1FCER2PDCD1 | |
| SCHEMBL9514815 | 0.84 | FFAR1 (0.43) | ALDH1A1MMP1FCER2L3MBTL1PDCD1 | |
| SCHEMBL7402132 | 0.84 | FFAR1 (0.43) | ALDH1A1MMP1FCER2L3MBTL1PDCD1 | |
| SCHEMBL8935368 | 0.82 | FFAR1 (0.51) | MEN1KMT2APPARGPPARAALDH1A1 | |
| SCHEMBL7397778 | 0.82 | FFAR1 (0.51) | MEN1KMT2APPARGPPARAALDH1A1 | |
| SCHEMBL9514811 | 0.78 | ALDH1A1 (0.44) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL7402130 | 0.78 | ALDH1A1 (0.44) | MEN1KMT2ANPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5502079-A | TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS | FARMITALIA CARLO ERBA S.R.L. (IT) | 1996-03-26 | — | — | US | disclosed |
| US-5391577-A | Active on central nervous system; antiepileptic agents | FARMITALIA CARLO ERBA S R L (IT) | 1995-02-21 | — | — | US | disclosed |
| US-5236957-A | Antiepileptic agents | FARMITALIA CARLO ERBA SRL (IT) | 1993-08-17 | — | — | US | disclosed |