Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.58 |
| ▸ | RXRA | P19793 | 1/20 | 0.56 |
| ▸ | RXRB | P28702 | 1/20 | 0.56 |
| ▸ | RXRG | P48443 | 1/20 | 0.56 |
| ▸ | MAOA | P21397 | 3/20 | 0.55 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.50 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.50 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.49 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8935303 | 0.86 | MAOB (0.54) | MAOBRXRARXRBRXRGMAOA | |
| SCHEMBL27312927 | 0.85 | PARP10 (0.56) | MAOBMAOAALOX5NR4A2 | |
| SCHEMBL8935328 | 0.84 | PKM (0.61) | MAOBRXRARXRBRXRGMAOA | |
| SCHEMBL8935444 | 0.81 | RXRA (0.60) | MAOBRXRARXRBRXRGMAOA | |
| SCHEMBL8935325 | 0.77 | PKM (0.57) | MAOBRXRARXRBRXRGMAOA | |
| SCHEMBL30398136 | 0.76 | MAOB (0.73) | MAOBRXRARXRBRXRGMAOA | |
| SCHEMBL9626627 | 0.76 | MAOB (0.73) | MAOBRXRARXRBRXRGMAOA | |
| SCHEMBL3969644 | 0.75 | MAOB (0.57) | MAOBRXRARXRBRXRGMAOA | |
| SCHEMBL4426731 | 0.75 | MAOB (0.63) | MAOBRXRARXRBRXRGMAOA | |
| SCHEMBL7398078 | 0.75 | MAOB (0.54) | MAOBRXRARXRBRXRGMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5502079-A | TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS | FARMITALIA CARLO ERBA S.R.L. (IT) | 1996-03-26 | — | — | US | disclosed |