Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | SI | P14410 | 1/20 | 0.41 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MYC | P01106 | 1/20 | 0.39 |
| ▸ | WDR5 | P61964 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15850505 | 0.84 | KDM4E (0.45) | NPC1RAB9AADORA2AADORA1ADORA3 | |
| SCHEMBL8935540 | 0.79 | DGAT1 (0.41) | NPC1RAB9AADORA2AADORA1GAA | |
| SCHEMBL544849 | 0.78 | CSNK1A1 (0.45) | NPC1RAB9AADORA2AADORA1ADORA3 | |
| SCHEMBL8935466 | 0.78 | KDM4E (0.41) | NPC1RAB9AADORA2AADORA1ADORA3 | |
| SCHEMBL10985672 | 0.75 | KDM4E (0.38) | NPC1RAB9AADORA2AADORA1ADORA3 | |
| SCHEMBL10981557 | 0.71 | MEN1 (0.44) | NPC1RAB9AKDM4EGAAMEN1 | |
| SCHEMBL8519653 | 0.69 | CA12 (0.46) | NPC1RAB9AKDM4EGAAMEN1 | |
| SCHEMBL7061715 | 0.68 | RAB9A (0.42) | NPC1RAB9AKDM4EGAAMEN1 | |
| SCHEMBL8789633 | 0.67 | MYC (0.50) | KDM4EGAAMEN1KMT2ANPSR1 | |
| SCHEMBL17921661 | 0.67 | CHRM1 (0.35) | KDM4ENOTUMGAAHTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5547920-A | Thiadizole derivatives and herbicide compositions containing the same | TOSOH CORPORATION (JP) | 1996-08-20 | — | — | US | disclosed |
| US-5500408-A | NONPHYTOTOXIC | TOSOH CORPORATION (JP) | 1996-03-19 | — | — | US | disclosed |
| US-5498593-A | Thiadiazole derivatives and herbicide compositions containing the same | TOSOH CORPORATION (JP) | 1996-03-12 | — | — | US | disclosed |
| US-5482916-A | APPLYING TO WEEDS AN ANTIGROWTH AGENTS | TOSOH CORPORATION (JP) | 1996-01-09 | — | — | US | disclosed |
| EP-0414511-A1 | Thiadiazole derivatives and herbicide compositions containing the same | Tosoh Corporation (JP) | 1991-02-27 | — | — | EP | disclosed |