Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | ANPEP | P15144 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3373290 | 0.78 | CYP2D6 (0.46) | CYP2D6MEN1RECQLKMT2ANOS3 | |
| SCHEMBL1515117 | 0.77 | NOS3 (0.41) | NOS3NOS1NOS2GRIN2BPLAU | |
| SCHEMBL5542044 | 0.75 | NOS3 (0.39) | CYP2D6MEN1RECQLKMT2ANOS3 | |
| SCHEMBL10388003 | 0.75 | NOS3 (0.39) | CYP2D6MEN1RECQLKMT2ANOS3 | |
| SCHEMBL8630301 | 0.75 | NOS3 (0.39) | CYP2D6MEN1RECQLKMT2ANOS3 | |
| SCHEMBL11647276 | 0.73 | NOS3 (0.39) | NOS3NOS1NOS2GRIN2BCYP19A1 | |
| SCHEMBL5008486 | 0.72 | NOS3 (0.42) | NOS3NOS1NOS2ANPEPPLAU | |
| SCHEMBL7137711 | 0.71 | HTR1A (0.41) | NOS3NOS1NOS2SIGMAR1 | |
| SCHEMBL6866536 | 0.69 | KDM4E (0.41) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL8663748 | 0.68 | HTR1A (0.36) | NOS3NOS1NOS2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8041006-A | — | — | None | — | — | JP | disclosed |
| JP-H0841006-A | DIUREA DERIVATIVE | NISSHIN FLOUR MILLING CO LTD | 1996-02-13 | — | — | JP | disclosed |