SCHEMBL8935568

SCHEMBL8935568

CC(C)CN(C(=S)SSC(=S)N(CC(C)C)c1ccccc1)c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 4/20 0.52
FAAH O00519 1/20 0.52
PHGDH O43175 1/20 0.52
ALDH1A1 P00352 3/20 0.41
GLA P06280 1/20 0.39
TSHR P16473 1/20 0.39
AOC3 Q16853 2/20 0.39
L3MBTL1 Q9Y468 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
MEN1 O00255 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
KMT2A Q03164 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
THRB P10828 1/20 0.35
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA9 Q16790 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7450023 0.80 ALDH1A1 (0.48) MGLLFAAHPHGDHALDH1A1GLA
SCHEMBL1024200 0.79 ALDH1A1 (0.57) MGLLFAAHPHGDHALDH1A1GLA
SCHEMBL30237945 0.76 MGLL (0.53) MGLLFAAHPHGDHALDH1A1GLA
SCHEMBL11404737 0.76 ALDH1A1 (0.52) ALDH1A1GLATSHRAOC3MEN1
SCHEMBL8121494 0.74 ALDH1A1 (0.50) ALDH1A1GLATSHRAOC3L3MBTL1
SCHEMBL30237836 0.74 MGLL (0.50) MGLLFAAHPHGDHALDH1A1GLA
SCHEMBL8121490 0.73 ALDH1A1 (0.48) ALDH1A1GLATSHRAOC3MEN1
SCHEMBL7379075 0.73 ALDH1A1 (0.48) ALDH1A1GLATSHRAOC3NPSR1
SCHEMBL5495426 0.73 ALDH1A1 (0.48) ALDH1A1GLATSHRAOC3MEN1
SCHEMBL15492964 0.71 ADRA2C (0.54) ALDH1A1GLATSHRMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5554699-A USING BRANCHED N-ALKYLDITHIOCARBAMYL DERIVATIVE ACCELERATORS THE B. F. GOODRICH COMPANY (US) 1996-09-10 US disclosed
EP-0591632-A2 Method of curing rubbers without forming nitrosamines THE B.F. GOODRICH COMPANY (US) 1994-04-13 EP disclosed