Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | HTR2A | P28223 | 2/20 | 0.49 |
| ▸ | HTR2B | P41595 | 2/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 4/20 | 0.43 |
| ▸ | PPARG | P37231 | 3/20 | 0.43 |
| ▸ | SCN4A | P35499 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8935768 | 1.00 | TDP1 (0.55) | TDP1CYP1A2CYP2C9KMT2AGAA | |
| SCHEMBL9500663 | 0.88 | TSHR (0.50) | TDP1CYP1A2CYP2C9KMT2AGAA | |
| SCHEMBL4748547 | 0.85 | TDP1 (0.45) | TDP1CYP1A2CYP2C9KMT2AGAA | |
| SCHEMBL23804881 | 0.81 | L3MBTL1 (0.45) | CYP1A2CYP2C9KMT2ATSHRHTR2A | |
| Hydrochloric Acid SCHEMBL2720751 | 0.81 | LMNA (0.44) | TDP1CYP1A2CYP2C9KMT2APKM | |
| SCHEMBL14988796 | 0.80 | TDP1 (0.55) | TDP1CYP1A2CYP2C9KMT2AGAA | |
| SCHEMBL14989117 | 0.80 | TDP1 (0.55) | TDP1CYP1A2CYP2C9KMT2AGAA | |
| SCHEMBL15122376 | 0.80 | TDP1 (0.55) | TDP1CYP1A2CYP2C9KMT2AGAA | |
| SCHEMBL9780698 | 0.78 | KMT2A (0.49) | TDP1CYP1A2CYP2C9KMT2AGAA | |
| SCHEMBL12310141 | 0.78 | KMT2A (0.68) | TDP1CYP1A2CYP2C9KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5491167-A | INHIBITORS OF CHOLESTEROL BIOSYNTHESIS | SANKYO COMPANY, LIMITED (JP) | 1996-02-13 | — | — | US | disclosed |