Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.57 |
| ▸ | HPGD | P15428 | 7/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.53 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | NSD2 | O96028 | 2/20 | 0.49 |
| ▸ | CFTR | P13569 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | FADS1 | O60427 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27753433 | 0.85 | ALDH1A1 (0.60) | ALDH1A1KDM4EHPGDHSD17B10RCE1 | |
| SCHEMBL31267447 | 0.84 | ALDH1A1 (0.68) | ALDH1A1KDM4EHPGDHSD17B10RCE1 | |
| SCHEMBL8745364 | 0.84 | ALDH1A1 (0.60) | ALDH1A1KDM4EHPGDHSD17B10RCE1 | |
| SCHEMBL11377492 | 0.81 | ALDH1A1 (0.57) | ALDH1A1KDM4EHPGDHSD17B10RCE1 | |
| SCHEMBL866062 | 0.81 | ALDH1A1 (0.64) | ALDH1A1KDM4EHPGDHSD17B10RCE1 | |
| SCHEMBL1202541 | 0.81 | ALDH1A1 (0.64) | ALDH1A1KDM4EHPGDHSD17B10RCE1 | |
| SCHEMBL1561753 | 0.80 | HPGD (0.66) | ALDH1A1KDM4EHPGDHSD17B10TP53 | |
| SCHEMBL112991 | 0.79 | ALDH1A1 (0.55) | ALDH1A1KDM4EHPGDHSD17B10RCE1 | |
| SCHEMBL31267470 | 0.79 | ALDH1A1 (0.62) | ALDH1A1KDM4EHPGDHSD17B10TP53 | |
| SCHEMBL3688021 | 0.79 | ALDH1A1 (0.62) | ALDH1A1KDM4EHPGDHSD17B10TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101189210-B | Sulfonamide derivatives useful as liver carnitine palmitoyl transferase (L-CPTl) inhibitors | HOFFMANN LA ROCHE | 2012-06-06 | — | — | CN | disclosed |
| EP-0651769-A4 | LEUKAEMIA INHIBITORY FACTOR-BINDING PROTEIN. | AMRAD CORP LTD (AU) | 1996-05-08 | — | — | EP | disclosed |
| EP-0651769-A1 | LEUKAEMIA INHIBITORY FACTOR-BINDING PROTEIN | AMRAD CORPORATION LIMITED (AU) | 1995-05-10 | — | — | EP | disclosed |
| WO-1994001464-A1 | LEUKAEMIA INHIBITORY FACTOR-BINDING PROTEIN | AMRAD CORPORATION LIMITED (AU) | 1994-01-20 | — | — | WO | disclosed |