SCHEMBL8745364

SCHEMBL8745364

Nc1ccccc1C(=O)NCNC(=O)c1ccccc1N

nearest known ligand 0.60

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 10/20 0.60
KDM4E B2RXH2 8/20 0.60
HPGD P15428 7/20 0.60
HSD17B10 Q99714 3/20 0.55
RCE1 Q9Y256 1/20 0.55
TP53 P04637 1/20 0.53
MAPK1 P28482 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
GAA P10253 2/20 0.52
CFTR P13569 1/20 0.52
NSD2 O96028 2/20 0.51
USP2 O75604 1/20 0.51
LMNA P02545 1/20 0.50
FADS1 O60427 1/20 0.50
NPC1 O15118 1/20 0.49
RAB9A P51151 1/20 0.49
MAPT P10636 1/20 0.48
PTGS1 P23219 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31267447 0.88 ALDH1A1 (0.68) ALDH1A1KDM4EHPGDHSD17B10RCE1
Octanedioate SCHEMBL15255207 0.87 ALDH1A1 (0.49) ALDH1A1KDM4EHPGDHSD17B10RCE1
SCHEMBL8935803 0.84 ALDH1A1 (0.57) ALDH1A1KDM4EHPGDHSD17B10RCE1
SCHEMBL866062 0.84 ALDH1A1 (0.64) ALDH1A1KDM4EHPGDHSD17B10RCE1
SCHEMBL1202541 0.84 ALDH1A1 (0.64) ALDH1A1KDM4EHPGDHSD17B10RCE1
SCHEMBL11377492 0.84 ALDH1A1 (0.57) ALDH1A1KDM4EHPGDHSD17B10RCE1
SCHEMBL112991 0.83 ALDH1A1 (0.55) ALDH1A1KDM4EHPGDHSD17B10RCE1
SCHEMBL196585 0.82 ALDH1A1 (0.55) ALDH1A1KDM4EHPGDHSD17B10RCE1
SCHEMBL31267470 0.82 ALDH1A1 (0.62) ALDH1A1KDM4EHPGDHSD17B10TP53
SCHEMBL3688021 0.82 ALDH1A1 (0.62) ALDH1A1KDM4EHPGDHSD17B10TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023144607-A1 POLYMERIC MATERIALS WITH REDUCED ALDEHYDE CONTENT AND PROCESS COLORMATRIX HOLDINGS, INC. (US) 2023-08-03 WO disclosed
EP-0596150-B1 Solutions of polyimide precursors BASF LACKE & FARBEN (DE) 1997-02-05 EP disclosed
EP-0596149-B1 Solutions of polyimide precursors BASF LACKE & FARBEN (DE) 1996-10-16 EP disclosed
US-5489644-A COMPRISING AROMATIC DIAMINES AND TETRAESTER OF AROMATIC TETRACARBOXYLIC ACID; PROTECTIVE COATING FOR METALS, SILICON WAFERS, GLASS BASF LACKE + FARBEN (DE) 1996-02-06 US disclosed
US-5474876-A Carboxyl-containing polymeric precursor of heterocyclic polymer which is stable at high temperatures and soluble in polar solvents, copolymerizable unsaturated tertiary sulfonium salt, photoinitiator, polar aprotic organic solvent BASF LACKE + FARBEN AG (DE) 1995-12-12 US disclosed
EP-0621299-A1 Solutions of polyimide-forming substances and their use as coating material BASF Lacke + Farben AG (DE) 1994-10-26 EP disclosed
US-5332799-A Aromatic diamines, diesters of aromatic tetracarboxylic acids, circuit coatings BASF LACKE+FARBEN AKTIENGESELLSCHAFT (DE) 1994-07-26 US disclosed
EP-0596150-A1 Solutions of polyimide precursors BASF Lacke + Farben Aktiengesellschaft (DE) 1994-05-11 EP disclosed
EP-0596149-A1 Solutions of polyimide precursors BASF Lacke + Farben Aktiengesellschaft (DE) 1994-05-11 EP disclosed
US-5264545-A Aromatic or partly aromatic diamine with tetracarboxylic acid BASF LACKE+FARBEN AKTIENGESELLSCHAFT (DE) 1993-11-23 US disclosed